Patents by Inventor Vasile Ionita-Manzatu
Vasile Ionita-Manzatu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7323198Abstract: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.Type: GrantFiled: July 27, 2005Date of Patent: January 29, 2008Assignee: Color Access, Inc.Inventors: Vasile Ionita-Manzatu, Mirela Ionita-Manzatu, Gheorghe Cicoa, Andrew J. Bevacqua
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Publication number: 20060275351Abstract: The invention relates to a delivery system for biologically active oligopeptides. The delivery system comprises an electrochemical cell and a skin-beneficial amount of one or more oligopeptides. In a preferred embodiment the electrochemical cell and the peptide are contained in a dermal patch. The invention also relates to a topically acceptable hydrogel that comprises a hydrophilic polymer, an aqueous or aqueous alcoholic carrier, at least one skin-beneficial oligopeptide, and a salt, wherein at least a portion of the carrier is a structured water.Type: ApplicationFiled: June 2, 2006Publication date: December 7, 2006Inventors: Fatemeh Mohammadi, Vasile Ionita-Manzatu, Andrew Bevacqua, Julius Zecchino, Anna Czarnota, Mirela Ionita-Manzatu
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Publication number: 20060088602Abstract: A cosmetic or pharmaceutical emulsion composition that is topically applied to the skin to protect it against damage caused by electromagnetic field generated from everyday appliances such as televisions, computers and cellular phones. The compositions contain ambient electromagnetic wave dampening effective amounts of at least one single domain magnet as the sole magnetic component and a non-magnetic ionic component. The sole magnetic component works particularly well in the composition of the present invention when it comprises granatite and when the composition is an oil in water emulsion.Type: ApplicationFiled: October 21, 2004Publication date: April 27, 2006Inventors: George Cioca, Paolo Glacomoni, Glen Rein, Vasile Ionita-Manzatu, Abdul Manirazman, Liliana George, Andrew Bevacqua, Harvey Gedeon
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Publication number: 20060003017Abstract: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.Type: ApplicationFiled: July 27, 2005Publication date: January 5, 2006Inventors: Vasile Ionita-Manzatu, Mirela Ionita-Manzatu, Gheorghe Cioca, Andrew Bevacqua
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Patent number: 6958163Abstract: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.Type: GrantFiled: June 27, 2002Date of Patent: October 25, 2005Assignee: Color Access, Inc.Inventors: Vasile Ionita-Manzatu, Mirela Ionita-Manzatu, Gheorghe Cioca, Andrew J. Bevacqua
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Patent number: 6905523Abstract: The invention relates to methods of coloring the hair with cluster-modified water and the ability to achieve enhanced color and conditioning for the hair that is color-treated. The cluster-modified water can be ionized water such as alkalinic or acidic water, or structured water such as I or S water. In addition, the cluster-modified water can be applied to the hair as a pre-saturating treatment and/or a post-saturating treatment relative to the hair color treatment process. Additional benefits of the present invention are the ability to minimize the use of harsh chemicals and dyes while still achieving an enriched color, and increased softness and smoothness to the color-treated hair. The present invention can also be used with mordanting salts. The present invention also includes a hair coloring kit including the cluster-modified water for post-saturating and/or pre-saturating the hair.Type: GrantFiled: March 13, 2003Date of Patent: June 14, 2005Assignees: Aveda Corporation, Color Access, Inc.Inventors: Alex Vainshelboim, Peter Matravers, Asira Ostrovskaya, Kimberly Switlick, Julie Dachtera, Vasile Ionita-Manzatu, George Cioca, Harvey Gedeon, Geoffrey Hawkins, Michael Hayes
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Publication number: 20050048089Abstract: The present invention relates to a topical system for application to the skin comprising an effective amount of a colloidal crystalline array in a hydrophilic phase, and at least one oil-containing phase.Type: ApplicationFiled: August 20, 2004Publication date: March 3, 2005Inventors: Daniela Bratescu, George Cioca, Lilliana George, Vasile Ionita-Manzatu, Charles Tadlock, Heather Bowen-Leaver
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Publication number: 20040177453Abstract: The invention relates to methods of coloring the hair with cluster-modified water and the ability to achieve enhanced color and conditioning for the hair that is color-treated. The cluster-modified water can be ionized water such as alkalinic or acidic water, or structured water such as I or S water. In addition, the cluster-modified water can be applied to the hair as a pre-saturating treatment and/or a post-saturating treatment relative to the hair color treatment process. Additional benefits of the present invention are the ability to minimize the use of harsh chemicals and dyes while still achieving an enriched color, and increased softness and smoothness to the color-treated hair. The present invention can also be used with mordanting salts. The present invention also includes a hair coloring kit including the cluster-modified water for post-saturating and/or pre-saturating the hair.Type: ApplicationFiled: March 13, 2003Publication date: September 16, 2004Inventors: Alex Vainshelboim, Peter Matravers, Asira Ostrovskaya, Kimberly Switlick, Julie Dachtera, Vasile Ionita-Manzatu, George Cioca, Harvey Gedeon, Geoffrey Hawkins, Michael Hayes
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Publication number: 20040043084Abstract: The present invention relates to a method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract. The invention also relates to the bioconverted material so prepared, and the use of same in cosmetic or pharmaceutical compositions.Type: ApplicationFiled: May 1, 2003Publication date: March 4, 2004Inventors: George Cioca, Vasile Ionita-Manzatu, Liliana George, Paolo U. Giacomoni, Andrew J. Bevacqua, Harvey Gedeon, Charles Craig Tadlock, Donald F. Collins, Thomas Mammone, Daniel H. Maes, Christina G. Fthenakis
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Publication number: 20020197335Abstract: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.Type: ApplicationFiled: June 27, 2002Publication date: December 26, 2002Inventors: Vasile Ionita-Manzatu, Mirela Ionita-Manzatu, Gheorghe Cioca, Andrew J. Bevacqua
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Publication number: 20020187203Abstract: The invention relates to structured water and the ability to achieve antimicrobial activity when the structured water has two antimicrobial agents in its cluster structure. One of the two antimicrobial agents can be stabilizing agent for the other antimicrobial agent. Thus, the antimicrobial structured water contains a combination of positively charged ions having antimicrobial activity and a stabilizing agent present within its cluster structure. In particular, the present invention relates to potassium sorbate and ionic silver incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the stabilizing agent and the positively charged ions incorporated within the cluster structure of structured water acts as a preservative when used in cosmetic or pharmaceutical compositions. The structured water of the present invention also has a stabilizing effect on the antimicrobial activity of the ionic silver.Type: ApplicationFiled: April 19, 2001Publication date: December 12, 2002Inventors: Gheorghe Cioca, Mirela Cristina Ionita-Manzatu, Steven F. Schnittger, Vasile Ionita-Manzatu, Andrew J. Bevacqua
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Patent number: 6451328Abstract: The invention relates to structured water and its antioxidant activity. In addition, the present invention relates to antioxidants incorporated within the cluster structure of either electropositive (S water) or electronegative (I water). The structured water, having the antioxidant within its cluster structure, has a stabilizing effect on the antioxidant. In addition, the antioxidant activity inherent to structured water is enhanced by the presence of the antioxidant within its cluster structure. The present invention also includes methods of removing or reducing free radicals on the skin and thereby preventing the signs of skin aging and the risks of cancer associated with the presence of free radicals in the skin.Type: GrantFiled: August 3, 2000Date of Patent: September 17, 2002Assignee: Color Access, Inc.Inventors: Vasile Ionita-Manzatu, Mirela Ionita-Manzatu, Gheorghe Cioca, Andrew J. Bevacqua
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Patent number: 6139855Abstract: The invention relates to composition having enhanced biological activity, the compositions comprising at least one structured water. In particular, the compositions contain a combination of I and S waters and a biologically active agent, in which the activity of the agent is increased relative to its activity in a non-structured water composition.Type: GrantFiled: February 1, 1999Date of Patent: October 31, 2000Assignee: Color Access, Inc.Inventors: Gheorghe Cioca, Joseph Gubernick, Andrew J. Bevacqua, Nicolae Vrabie, Daniel H. Maes, Kenneth D. Marenus, Edward Pelle, Neelam Muizzuddin, Vasile Ionita-Manzatu, Mirela Cristina Ionita-Manzatu
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Patent number: 5965151Abstract: This bioactive concentrate is an active substance--aqueous solution or lyophilized powder--consisting of anti-hyaluronidase and antiinflammatory mucopolysaccharide polymers and an addition of restitutive and anti-hyaluronidase chondroitinsulphate, which has a pH=4-6 and antihyaluronidase activity. The bioactive concentrate producing method consists in a two--phased treatment of animal--originated connective cartilaginous tissues such as bovine and sheep trachea, umbilical cord, young animal tendons, bowels, testicles or sea organisms, with phenol solution and the solution resulted is concentrated by vacuum evaporation and then defatted; after filtering, the supernatant obtained is treated for deproteinization, the ion excess is removed by passing through ion exchanger column, the alcohol solution is concentrated to remove alcohol until reaching a volume of 70% as against the aqueous solution subject to proteinzation.Type: GrantFiled: October 3, 1997Date of Patent: October 12, 1999Assignee: S. C. Tehman S.R.L.Inventors: Ioan Manzatu, Dan-Etienne Arizan, Vasile Ionita-Manzatu, Marian Carasava, Maria Panait, Irina-Gabriela Scarlat
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Patent number: 5846397Abstract: An apparatus is disclosed for obtaining inhibitively active "I" water and stimulatively activated "S" water which comprises:a parallelipipedic column having an open top;a support for said column;a cover closing said top of said column;at least one electrode assembly in said column and including:a pair of spaced apart mutually parallel porous membranes defining between inner surfaces thereof a supply space receiving water to be separated into inhibitively activated "I" water and stimulatively activated "S" water,respective porous electrodes spaced from outer surfaces of said membranes and parallel thereto, anda respective spacer between each of said electrodes and the respective outer surface whereby water flows outwardly from said supply space through said membranes and said electrodes;means for electrically connecting one of said electrodes as a positive electrode and the other of said electrodes as a negative electrode;means in said column for forming a first storage space adjacent said positive electrode fType: GrantFiled: February 10, 1997Date of Patent: December 8, 1998Assignee: S. C. TehmanInventors: Ioan Manzatu, Vasile Ionita-Manzatu