Patents by Inventor Vasileios PETROU

Vasileios PETROU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rational drug design targeting resistant gram-negative bacterial infections to polymyxin-class antibiotics
    Patent number: 10925857
    Abstract: The present invention relates to identification of inhibitors or antagonists of aminoarabinase glycosyltransferase (ArnT) and their use in compositions, methods of treatment or prevention of drug resistant gram negative infections, or inhibiting the growth of gram negative bacterial infections resistant to polymyxin-class antibiotics. In certain aspects, the inhibitors or antagonists can be administered in combination with one or more antibacterial agents.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: February 23, 2021
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Filippo Mancia, Vasileios Petrou, Oliver B. Clarke, Jeremie P. Vendome
  • RATIONAL DRUG DESIGN TARGETING RESISTANT GRAM-NEGATIVE BACTERIAL INFECTIONS TO POLYMYXIN-CLASS ANTIBIOTICS
    Publication number: 20190231747
    Abstract: The present invention relates to identification of inhibitors or antagonists of aminoarabinase glycosyltransferase (ArnT) and their use in compositions, methods of treatment or prevention of drug resistant gram negative infections, or inhibiting the growth of gram negative bacterial infections resistant to polymyxin-class antibiotics. In certain aspects, the inhibitors or antagonists can be administered in combination with one or more antibacterial agents.
    Type: Application
    Filed: November 14, 2016
    Publication date: August 1, 2019
    Inventors: Filippo MANCIA, Vasileios PETROU, Oliver B. CLARKE, Jeremie P. VENDOME