Patents by Inventor Vassil S. Georgiev

Vassil S. Georgiev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6596771
    Abstract: A series of imidodisulfamide derivatives have been prepared and are useful to treat antiviral infections, especially infections caused by orthopox viruses.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: July 22, 2003
    Assignee: Schering Corporation
    Inventor: Vassil S. Georgiev
  • Publication number: 20020193443
    Abstract: A series of imidodisulfamide derivatives have been prepared and are useful to treat antiviral infections, especially infections caused by orthopox viruses.
    Type: Application
    Filed: July 1, 2002
    Publication date: December 19, 2002
    Inventor: Vassil S. Georgiev
  • Patent number: 4871862
    Abstract: .alpha.-Substituted ketonitrone derivatives containing substituents selected from hydrogen, phenyl, substituted phenyl, naphthyl, furan, thiophen, imidazolylmethyl and triazolylmethyl are useful as intermediates for the preparation of biologically active isoxazolidine compounds.
    Type: Grant
    Filed: October 6, 1988
    Date of Patent: October 3, 1989
    Assignee: Fisons Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4845122
    Abstract: As an anti-allergic treatment for warm-blooded animals, therapeutic amounts of a compound having the formula I (including acid salts thereof) or II are administered: ##STR1## where; R is OR.sup.4 or NHR.sup.5 in which R.sup.4 is hydrogen or lower alkyl, R.sup.5 is selected from phenyl and phenyl monosubstituted with halogen, lower alkyl, lower alkoxy, R.sup.1 and R.sup.2 are independently hydrogen or lower alkyl, andR.sup.3 is selected from lower alkyl, arylcyclopropyl, naphthyl, phenyl, and phenyl monosubstituted with lower alkyl, lower alkoxy, trifluoromethyl, halogen, nitro, carboxyl, or ethyl carboxylate; ##STR2## R.sup.6 is lower alkyl, R.sup.7 is selected from phenyl and phenyl monosubstituted with lower alkyl, lower alkoxy, halogen or acetyl, and M is an alkali or alkaline earth metal.
    Type: Grant
    Filed: December 5, 1986
    Date of Patent: July 4, 1989
    Inventors: Vassil S. Georgiev, Clyde R. Kinsolving, Robert A. Mack
  • Patent number: 4835283
    Abstract: This invention pertains generally to substituted 2-methylisoxazolines and more specifically to 3,5-diphenyl-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-yl-methyl)]-2-methyl-4-isoxazoline derivatives which are useful as antifungal agents.
    Type: Grant
    Filed: March 7, 1988
    Date of Patent: May 30, 1989
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4831154
    Abstract: 5-alkyl(or alkenyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl) -2- methylisoxazolidines and related derivatives in which hydrogens of their phenyl rings can be replaced by halogen, lower alkyl or lower alkoxy groups are useful as antifugal agents.
    Type: Grant
    Filed: April 10, 1987
    Date of Patent: May 16, 1989
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4785117
    Abstract: 5,5-Disubstituted-3-phenyl-3-[(1H-imidazol-1-ylmethyl) or (1H-1,2,4-triazol-1-ylmethyl)]-2-methylisoxazolidine derivatives are useful as antifungal agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: November 15, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4777263
    Abstract: 5-Substituted-3-(2-naphthalenyl)-3-[(1H-imidazol-1-ylmethyl or (1H-1,2,4-triazol-1-ylmethyl)]-2-methylisoxazolidines are useful as antifungal agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: October 11, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4777262
    Abstract: 5-(Substituted thiomethyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidine derivatives are useful as antifungal agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: October 11, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4777264
    Abstract: 5-Carbonyl derivatives of 3-phenyl-3-(1-H-imidazol-1-ylmethyl)-2-methylisoxazolidines and related compounds are useful as antifungal agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: October 11, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4774334
    Abstract: Compounds possessing antiallergy activity have the formula: ##STR1## wherein R and R.sup.1 are independently hydrogen or alkyl, or R and R.sup.1 together with the attached nitrogen form a heterocyclic ring system selected from the group consisting of piperidinyl, pyrrolidinyl, morpholinyl and 1, 2, 3, 4-tetrohydroquinolinyl, and R.sup.2 is phenyl or phenyl monosubstituted with a lower alkyl, a nitro, a halogenated methyl, a halogen or a lower alkoxy group.
    Type: Grant
    Filed: November 9, 1987
    Date of Patent: September 27, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, Thomas R. DeCory
  • Patent number: 4769471
    Abstract: Substituted 3,5-diphenyl-3-[(1H-1,2,4-triazol-1-yl) methyl]-2-methylisoxazolidines in which hydrogens of their phenyl rings may be replaced by halogen, lower alkoxy, lower alkyl or nitro groups are useful as antifungal agents.
    Type: Grant
    Filed: April 10, 1987
    Date of Patent: September 6, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4769469
    Abstract: 5-(phenyl or phenoxymethyl)-3-(2-furanyl)-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolid ine and related derivatives in which one or more hydrogens on the phenyl ring are replaced by halogen, lower alkyl, lower alkoxy, nitro and combinations thereof are useful as antifungal agents.
    Type: Grant
    Filed: April 10, 1987
    Date of Patent: September 6, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4769470
    Abstract: 5-(Phenyl or phenoxymethyl)-3-(2-thienyl)-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolid ines and related derivatives in which one or more hydrogens on the 5-phenyl or phenoxy rings are replaced by halogen, lower alkyl, lower alkoxy, nitro and combinations thereof are useful as antifungal agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: September 6, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4769468
    Abstract: Alkyl and aryl ester compounds, 5-(acyloxyalkyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidine s in which hydrogens of their phenyl rings may be replaced by halogen, lower alkyl, lower alkoxy or nitro groups are useful as antifungal agents.
    Type: Grant
    Filed: April 10, 1987
    Date of Patent: September 6, 1988
    Assignee: Penwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4767868
    Abstract: 3-Phenyl-3-(1H-imidazol-1-ylmethyl)-2-methyl-5-[(phenylamino)methyl]isoxazo lidine and related derivatives in which hydrogens of their phenyl rings may be replaced by one or more halogen, lower alkoxy, lower alkyl and nitro groups are useful as antifungal agents.
    Type: Grant
    Filed: April 10, 1987
    Date of Patent: August 30, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4767867
    Abstract: 5-(Hydroxy or alkoxyalkyl)-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methylisoxazolidines and related derivatives in which hydrogens of the phenyl ring are replaced by halogen, lower alkyl or lower alkoxy groups are useful as antifungal agents.
    Type: Grant
    Filed: April 10, 1987
    Date of Patent: August 30, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4767866
    Abstract: 3-Phenyl-3-(1H-1,2,4-triazol-1-methyl)-2-methyl-5-alkylisoxazolidines and related derivatives in which hydrogens in the phenyl ring are replaced by halogen, lower alkyl or lower alkoxy groups are useful as antifungal agents.
    Type: Grant
    Filed: April 10, 1987
    Date of Patent: August 30, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen
  • Patent number: 4762828
    Abstract: 1,2,4-Triazolo[4,3-d]-4-azatricyclo[4.3.1.1.sup.3,8 ]-undecane and 3-derivatives and intermediates thereof are described. The compounds are useful and antiinflammatory and antihypoxia agents.
    Type: Grant
    Filed: June 10, 1987
    Date of Patent: August 9, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, Grace A. Bennett
  • Patent number: 4754042
    Abstract: 5-{[Naphthyl(or 2-oxo-1,3-benzoxathiol-6-yl)oxy]methyl}-3-phenyl-3-(1H-imidazol-1-ylmethyl )-2-methylisoxazolidines are useful as antifungal agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: June 28, 1988
    Assignee: Pennwalt Corporation
    Inventors: Vassil S. Georgiev, George B. Mullen