Abstract: The invention relates to platinum complexes of the following general formula: ##STR1## wherein R.sub.1 and R.sub.2 represent alkyl radicals with 1 to 18 carbon atoms, or R.sub.1 or R.sub.2 represent a hydrogen atom and R.sub.2 or R.sub.1 can represent an alkyl radical or a ##STR2## in which R.sub.3 is a hydrogen atom or the ##STR3## radical or an acyl radical, and x=1 or 2. These compounds can be produced by reaction of an alcohol solution of a 5,8-dihydroxyl-1,4-naphthoquinone of the following formula: ##STR4## in which the substituents R.sub.1 and R.sub.2 have the aforementioned meanings, in the presence of a concentrated aqueous ammonia solution, which adjusts the pH over 7, with K.sub.2 PtCl.sub.4 at room temperature. These platinum complex compounds are characterized by a good antitumor effect with low toxicity.

Abstract: Diplatinum complexes of the formulas ##STR1## wherein X and Y are ligands, such as Cl and/or NH.sub.3, having antineoplastic activity.

Abstract: The present invention provides a composition suitable for external application against skin injuries and diseases, such as ulcera, [e.g., Ulcus Cruris (indolent leg ulcer)], burns, scalds, open skin wounds, and the like, and having as its active ingredient a compound of the general formula ##STR1## wherein Y is hydrogen or --OX in which X represents hydrogen, a carboxylic acid residue, or a derivative of a carboxylic acid residue, and R.sub.1 and R.sub.2 are alkyl groups, e.g., lower alkyl groups such as methyl, and mixtures of these compounds. The most active of these ingredients is the compound of the above formula wherein X is the acetyl ester of the 3-methyl-3-hydroxy-butanecarboxylic acid residue. When mixtures of compounds including said most active compound of said general formula are employed against the aforesaid skin injuries and diseases, a synergistic effect is obtained.