Patents by Inventor Vasudevan Natarajan

Vasudevan Natarajan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of ivacaftor
    Patent number: 11274081
    Abstract: The present disclosed an improved process for the synthesis of ivacaftor starting from indole acetic acid ester which can be performed in batch as well as continuous flow synthesis. The present invention further disclosed to a continuous process for the synthesis of compound of formula (II) or formula (III) from compound of formula (I) in continuous flow reactor.
    Type: Grant
    Filed: May 26, 2017
    Date of Patent: March 15, 2022
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Dumbala Srinivasa Reddy, Amol Arvind Kulkarni, Vasudevan Natarajan, Mrityunjay Keshavprasad Sharma
  • AN IMPROVED PROCESS FOR THE SYNTHESIS OF IVACAFTOR
    Publication number: 20200325104
    Abstract: The present disclosed an improved process for the synthesis of ivacaftor starting from indole acetic acid ester which can be performed in batch as well as continuous flow synthesis. The present invention further disclosed to a continuous process for the synthesis of compound of formula (II) or formula (III) from compound of formula (I) in continuous flow reactor.
    Type: Application
    Filed: May 26, 2017
    Publication date: October 15, 2020
    Inventors: Dumbala Srinivasa REDDY, Amol Arvind KULKARNI, Vasudevan NATARAJAN, Mrityunjay Keshavprasad SHARMA
  • Process for the synthesis of ivacaftor and related compounds
    Patent number: 10336703
    Abstract: The present patent discloses a novel one pot two-step process for the synthesis of ivacaftor and related compounds of [Formula (I)], wherein R1, R2, R3, R4, R5, R6, R7 and Ar1 are as described above; its tautomers or pharmaceutically acceptable salts thereof starting from indole acetic acid amides.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: July 2, 2019
    Assignee: Council of Scientific and Industrial Research
    Inventors: Dumbala Srinivasa Reddy, Vasudevan Natarajan, Gorakhnath Rajaram Jachak
  • PROCESS FOR THE SYNTHESIS OF IVACAFTOR AND RELATED COMPOUNDS
    Publication number: 20180127373
    Abstract: The present patent discloses a novel one pot two-step process for the synthesis of ivacaftor and related compounds of [Formula (I)], wherein R1, R2, R3, R4, R5, R6, R7 and Ar1 are as described above; its tautomers or pharmaceutically acceptable salts thereof starting from indole acetic acid amides.
    Type: Application
    Filed: May 12, 2016
    Publication date: May 10, 2018
    Inventors: Dumbala Srinivasa Reddy, Vasudevan Natarajan, Gorakhnath Rajaram Jachak
  • Solomonamide analogue compounds, pharmaceuticals containing solomonamide analogue compounds, and processes for the preparation thereof
    Patent number: 9751911
    Abstract: Solomanamide analogs of Formula-I having anti-inflammatory activity, and viable synthetic routes for the preparation of such analogs, including the synthesis of macrocyclic core of Salomanamide analogs. The Solomanamide analogs of Formula-I or their pharmaceutical salt may be provided in a pharmaceutical composition and administered in an effective amount for the treatment of inflammation and/or pain.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: September 5, 2017
    Assignee: Council of Scientific and Industrial Research
    Inventors: Dumbala Srinivasa Reddy, Kashinath Komirishetty, Vasudevan Natarajan
  • SOLOMONAMIDE ANALOGUE COMPOUNDS, PHARMACEUTICALS CONTAINING SOLOMONAMIDE ANALOGUE COMPOUNDS, AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20150291659
    Abstract: Solomanamide analogues of Formula-I having anti-inflammatory activity, and viable synthetic routes for the preparation of such analogues, including the synthesis of macrocyclic core of Salomanamide analogues. The Solomanamide analogues of Formula-I or their pharmaceutical salt may be provided in a pharmaceutical composition and administered in an effective amount for the treatment of inflammation and/or pain.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 15, 2015
    Inventors: Dumbala Srinivasa Reddy, Kashinath Komirishetty, Vasudevan Natarajan