Patents by Inventor Vasudha Murlidhar

Vasudha Murlidhar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETECTING PROTEINS AND FOR CO-DETECTING PROTEINS AND NUCLEIC ACIDS, AND KITS FOR THE SAME
    Publication number: 20240035073
    Abstract: Disclosed herein are methods for detecting a target protein in a sample and methods for detecting a target protein and a target nucleic acid in a sample. Kits for carrying out the methods are also disclosed.
    Type: Application
    Filed: July 27, 2023
    Publication date: February 1, 2024
    Inventors: Xiao-Jun Ma, Bingqing Zhang, Henry Lamparski, Courtney Todorov, Lydia Hernandez, Vasudha Murlidhar, Haiyan Wu, HaYeun Ji, Emerald Doolittle, Maithreyan Srinivasan, Li-chong Wang
  • System for detecting rare cells
    Patent number: 10317406
    Abstract: A system for detecting rare cells in a fluid is disclosed. The system includes a substrate and a mixture disposed on the substrate and including a carrier and a thermo-responsive polymer for capture and release of the rare cells. Also disclosed is a method for detecting rare cells in a fluid using a system including a substrate and a mixture that is disposed on the substrate. The mixture includes a carrier and a thermo-responsive polymer. The method includes providing the system and introducing a sample of fluid containing the rare cells into the system such that the sample interacts with the carrier for capturing the rare cells.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: June 11, 2019
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Hyeun Joong Yoon, Apoorv Shanker, Jinsang Kim, Sunitha Nagrath, Vasudha Murlidhar
  • System for detecting rare cells
    Patent number: 10130946
    Abstract: This disclosure provides a system for detecting rare cells. The system includes a substrate, extensions extending outwardly from the substrate and arranged about a center axis of the substrate to define a channel enabling the fluid to move radially from the center axis to an outer edge of the substrate, and a functionalized graphene oxide disposed on the extension. This disclosure also provides a method for detecting rare cells using the system of this disclosure. The method includes the steps of introducing a sample of fluid containing the rare cells into the inlet of the system such that the sample of fluid flows radially from the inlet toward the outer edge of the substrate and capturing the rare cells as the rare cells interact with the functionalized graphene oxide disposed on the extensions.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: November 20, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Sunitha Nagrath, Vasudha Murlidhar
  • System for Detecting Rare Cells
    Publication number: 20160291019
    Abstract: A system for detecting rare cells in a fluid is disclosed. The system includes a substrate and a mixture disposed on the substrate and including a carrier and a thermo-responsive polymer for capture and release of the rare cells. Also disclosed is a method for detecting rare cells in a fluid using a system including a substrate and a mixture that is disposed on the substrate. The mixture includes a carrier and a thermo-responsive polymer. The method includes providing the system and introducing a sample of fluid containing the rare cells into the system such that the sample interacts with the carrier for capturing the rare cells.
    Type: Application
    Filed: April 6, 2016
    Publication date: October 6, 2016
    Inventors: Hyeun Joong Yoon, Apoorv Shanker, Jinsang Kim, Sunitha Nagrath, Vasudha Murlidhar
  • System for detecting rare cells
    Publication number: 20150285808
    Abstract: This disclosure provides a system for detecting rare cells. The system includes a substrate, extensions extending outwardly from the substrate and arranged about a center axis of the substrate to define a channel enabling the fluid to move radially from the center axis to an outer edge of the substrate, and a functionalized graphene oxide disposed on the extension. This disclosure also provides a method for detecting rare cells using the system of this disclosure. The method includes the steps of introducing a sample of fluid containing the rare cells into the inlet of the system such that the sample of fluid flows radially from the inlet toward the outer edge of the substrate and capturing the rare cells as the rare cells interact with the functionalized graphene oxide disposed on the extensions.
    Type: Application
    Filed: April 6, 2015
    Publication date: October 8, 2015
    Inventors: Sunitha Nagrath, Vasudha Murlidhar