Patents by Inventor Vasyl Andrushko

Vasyl Andrushko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11472770
    Abstract: The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, as in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrateand crystalline (S)-3-aminopiperidine-dihydrochloride-monohydrate.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: October 18, 2022
    Inventors: Karl Reuter, Tobias Wedel, Viktor Meier, Mark Kantor, Vasyl Andrushko, Florian Stolz
  • Publication number: 20220243008
    Abstract: Crystalline solvate forms and amorphous forms of 6,6?-diphenyl-2,2?-bis(2-hydroxyethoxy)-1,1?-binaphthyl, where the organic solvent is selected from methanol, toluene, and methyl ethyl ketone, and an amorphous form of 6,6?-diphenyl-2,2?-bis(2-hydroxyethoxy)-1,1?-binaphthyl having a purity of at least 99.0% by weight, based on organic matter. Thermoplastic resins containing a structural unit derived from 6,6?-diphenyl-2,2?-bis(2-hydroxyethoxy)-1,1?-binaphthyl. Optical lenses containing the thermoplastic resins containing a structural unit derived from 6,6?-diphenyl-2,2?-bis(2-hydroxyethoxy)-1,1?-binaphthyl.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 4, 2022
    Applicant: MITSUBISHI GAS CHEMICAL COMPANY, INC.
    Inventors: Shinya IKEDA, Noriyuki KATO, Manabu HIRAKAWA, Karl REUTER, Vasyl ANDRUSHKO, Mark KANTOR, Florian STOLZ
  • Publication number: 20220145004
    Abstract: Provided is a thermoplastic resin including constituent units represented by general formula (1). (In formula (1), R1 and R2 each independently represent: a hydrogen atom; a fluorine atom; a chlorine atom; a bromine atom; an iodine atom; a C1-6 alkyl group; a monocyclic or polycyclic C6-36 aryl group; a monocyclic or polycyclic heteroaryl group having 5-36 ring atoms, 1, 2, 3, or 4 of the ring atoms being selected from nitrogen, sulfur, and oxygen, and the other ring atoms being carbon in the heteroaryl group; a C2-6 alkenyl group; a C1-6 alkoxy group; or a C7-17 aralkyl group. In formula (1), X, a, and bare each as described in the present specification.
    Type: Application
    Filed: February 27, 2020
    Publication date: May 12, 2022
    Applicant: MITSUBISHI GAS CHEMICAL COMPANY, INC.
    Inventors: Shinya IKEDA, Noriyuki KATO, Manabu HIRAKAWA, Karl REUTER, Vasyl ANDRUSHKO, Mark KANTOR, Florian STOLZ
  • Publication number: 20210371367
    Abstract: The present invention relates to triarylmethane compounds of the formula (I), which suitable as monomers for preparing thermoplastic resins having beneficial optical properties and which can be used for producing optical devices. R1, R2 are e.g. hydrogen; Y is an alkylene group having 2, 3 or 4 carbon atoms, Ar is selected from mono- or polycyclic aryl and mono- or polycyclic hetaryl; X1, X2, X3, X4 are CH, C—Rx or N, provided that in each ring at most two of X1, X2, X3, X4 are N; Rx is e.g. halogen, CN or CH?CH2. The invention also relates to thermoplastic resins comprising a polymerized unit of the compound of formula (I).
    Type: Application
    Filed: February 1, 2019
    Publication date: December 2, 2021
    Applicant: MITSUBISHI GAS CHEMICAL COMPANY, INC.
    Inventors: Karl Reuter, Vasyl Andrushko, Mark Kantor, Florian Stolz, Munenori Shiratake, Kentaro Ishihara, Koji Hirose, Shinya Ikeda, Noriyuki Kato, Mitsuteru Kondo, Shoko Suzuki, Kensuke Oshima
  • Publication number: 20210340317
    Abstract: The present invention relates to compounds of the formula (I), which are suitable as monomers for preparing thermoplastic resins having beneficial optical properties and which can be used for producing optical devices. In Formula (I), A1, A2 are selected from mono- or bicyclic aromatic radicals and mono- or bicyclic heteroaromatic radicals; X represents e.g. a single bond, O, NH, CR6R7; Y is e.g. absent or represents a single bond, O, NH, CR8R9; R1, R2 are hydrogen, a radical Ar? or a radical Ra; R3 is Alk, O-Alk?-, O-Alk?-[O-Alk?]o, O—CH2—Ar—C(O)—, O—C(O)—Ar—C(O)— or O-Alk-C(O)—, where in the last five moieties the left O is bound to A1 and A2, respectively; m, n are 0, 1 or 2; o is an integer from 1 to 10; R4, R5 are e.g. selected from CN and a radical Ra; R6, R8 are e.g. selected from hydrogen, a radical Ar? and a radical Ra; R7, R9 are e.g. selected from hydrogen, C1-C4-alkyl and a radical Ar?; Ra is selected from the group consisting of C?C—R11 and Ar—C?C—R11; R11 is e.g.
    Type: Application
    Filed: October 18, 2019
    Publication date: November 4, 2021
    Inventors: Karl REUTER, Vasyl ANDRUSHKO, Mark KANTOR, Florian STOLZ, Philipp KOSCHKER, Munenori SHIRATAKE, Kentaro ISHIHARA, Koji HIROSE, Shinya IKEDA, Noriyuki KATO, Mitsuteru KONDO, Shoko SUZUKI, Kensuke OSHIMA
  • Patent number: 11072573
    Abstract: The present invention relates to binaphthyl compounds of the formula (I), which are suitable as monomers for preparing polycarbonate resins having beneficial optical properties and which can be used for producing optical lenses: Formula (I) where X is C2-C4-alkandiyl or C1-C4-alkandiyl-C(O)—, where C(O) is bound to the oxygen atom of the hydroxyl group and where C2-C4-alkandiyl or C1-C4-alkandiyl, respectively, are unsubstituted or carry a phenyl ring; R and R? are identical or different and selected from mono or polycyclic aryl having from 6 to 36 carbon atoms and mono- or polycyclic hetaryl having a total of 5 to 36 atoms, which are ring members, where 1, 2, 3 or 4 of these atoms are selected from nitrogen, sulfur and oxygen, while the remainder of these atoms are carbon atoms, where mono- or polycyclic aryl and mono- or polycyclic hetaryl are unsubstituted or carry 1 or 2 radicals Ra, which are selected from the group consisting of CN, CH3, OCH3, O-phenyl, O-naphthyl, S-phenyl, S-naphthyl, CI or F; and, if
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: July 27, 2021
    Assignee: Reuter Chemische Apparatebau E.K.
    Inventors: Karl Reuter, Vasyl Andrushko, Mark Kantor, Florian Stolz, Noriyuki Kato, Mitsuteru Kondo, Munenori Shiratake, Kentaro Ishihara, Shinya Ikeda, Shoko Suzuki, Koji Hirose, Kensuke Oshima, Shuya Nagayama
  • Publication number: 20200354299
    Abstract: The present invention relates to binaphthyl compounds of the formula (I), which are suitable as monomers for preparing polycarbonate resins having beneficial optical properties and which can be used for producing optical lenses: Formula (I) where X is C2-C4-alkandiyl or C1-C4-alkandiyl-C(O)—, where C(O) is bound to the oxygen atom of the hydroxyl group and where C2-C4-alkandiyl or C1-C4-alkandiyl, respectively, are unsubstituted or carry a phenyl ring; R and R? are identical or different and selected from mono or polycyclic aryl having from 6 to 36 carbon atoms and mono- or polycyclic hetaryl having a total of 5 to 36 atoms, which are ring members, where 1, 2, 3 or 4 of these atoms are selected from nitrogen, sulfur and oxygen, while the remainder of these atoms are carbon atoms, where mono- or polycyclic aryl and mono- or polycyclic hetaryl are unsubstituted or carry 1 or 2 radicals Ra, which are selected from the group consisting of CN, CH3, OCH3, O-phenyl, O-naphthyl, S-phenyl, S-naphthyl, CI or F; and, if
    Type: Application
    Filed: August 29, 2018
    Publication date: November 12, 2020
    Inventors: Karl REUTER, Vasyl ANDRUSHKO, Mark KANTOR, Florian STOLZ, Noriyuki KATO, Mitsuteru KONDO, Munenori SHIRATAKE, Kentaro ISHIHARA, Shinya IKEDA, Shoko SUZUKI, Koji HIROSE, Kensuke OSHIMA, Shuya NAGAYAMA
  • Publication number: 20200087257
    Abstract: The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, as in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrateand crystalline (S)-3-aminopiperidine-dihydrochloride-monohydrate.
    Type: Application
    Filed: September 23, 2019
    Publication date: March 19, 2020
    Applicant: REUTER CHEMISCHE APPARATEBAU KG
    Inventors: Karl Reuter, Tobias Wedel, Viktor Meier, Mark Kantor, Vasyl Andrushko, Florian Stolz
  • Patent number: 10464898
    Abstract: The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, and in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrate and crystalline (S)-3-aminopiperidine-di-hydrochloride-monohydrate.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: November 5, 2019
    Assignee: Reuter Chemische Apparatebau KG
    Inventors: Karl Reuter, Tobias Wedel, Viktor Meier, Mark Kantor, Vasyl Andrushko, Florian Stolz
  • Publication number: 20160251311
    Abstract: The present invention relates to a process for the preparation of enantiomerically enriched 3-aminopiperidine, and in particular of its R-enantiomer (R)-3-aminopiperidine. The invention also relates to an enantiomerically enriched intermediate of said process and to specific acid-addition salts of 3-aminopiperidine (hereinafter also APIP) that are useful for obtaining a single enantiomer of APIP, and to crystalline (R)-3-aminopiperidine-dihydrochloride-monohydrate and crystalline (S)-3-aminopiperidine-di-hydrochloride-monohydrate.
    Type: Application
    Filed: February 19, 2014
    Publication date: September 1, 2016
    Applicant: REUTER CHEMISCHE APPARATEBAU KG
    Inventors: Karl Reuter, Tobias Wedel, Viktor Meier, Mark Kantor, Vasyl Andrushko, Florian Stolz
  • Publication number: 20160068486
    Abstract: The present invention relates to a process for preparing enantiomerically enriched 3-hydroxymethylpiperidine and in particular of the S-enantiomer of (S)-3-hydroxymethyl-piperidine in high chemical and optical purity. The invention also relates to extremely pure (S)-3-hydroxymethylpiperidine and (R)-3-hydroxymethylpiperidine.
    Type: Application
    Filed: April 22, 2014
    Publication date: March 10, 2016
    Applicant: REUTER CHEMISCHE APPARATEBAU KG
    Inventors: Karl Reuter, Tobias Wedel, Vasyl Andrushko, Christian Wiegand, Florian Stolz
  • Publication number: 20110295005
    Abstract: The present invention relates to a process for preparing pyrimidine derivatives of the formula V, in particular as intermediates useful for preparing pyrimidine derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, such as HMG-CoA reductase inhibitors, e.g. rosuvastatin.
    Type: Application
    Filed: August 19, 2008
    Publication date: December 1, 2011
    Applicant: Ratiopharm GmbH
    Inventors: Armin Boerner, Gerd Koenig, Natalia Andrushko, Vasyl Andrushko
  • Publication number: 20110065920
    Abstract: The present invention relates to a process for preparing pentanoic diacid derivatives useful for preparing pyrimidine derivatives, in particular as intermediates useful for preparing pyrimidine derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, such as HMG-CoA reductase inhibitors, e.g. rosuvastatin.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 17, 2011
    Applicant: ratiopharm GmbH
    Inventors: Armin Boerner, Gerd Koenig, Natalia Andrushko, Vasyl Andrushko