Patents by Inventor Vaughn V. Smider

Vaughn V. Smider has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RAPID ELICITATION OF BROADLY NEUTRALIZING BOVINE ANTIBODIES TO HIV ENV
    Publication number: 20240109956
    Abstract: The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab?)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
    Type: Application
    Filed: September 19, 2023
    Publication date: April 4, 2024
    Inventors: Devin SOK, Dennis R. BURTON, Vaughn V. SMIDER, Ian WILSON, Michael CRISCITIELLO, Waithaka MWANGI
  • Rapid elicitation of broadly neutralizing antibodies to HIV Env
    Patent number: 11795211
    Abstract: The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab?)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: October 24, 2023
    Assignees: International AIDS Vaccine Initiative, The Scripps Research Institute, THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Devin Sok, Dennis R. Burton, Vaughn V. Smider, Ian Wilson, Michael Criscitiello, Waithaka Mwangi
  • RAPID ELICITATION OF BROADLY NEUTRALIZING ANTIBODIES TO HIV ENV
    Publication number: 20200165324
    Abstract: The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab?)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.
    Type: Application
    Filed: July 12, 2018
    Publication date: May 28, 2020
    Inventors: Devin SOK, Dennis R. BURTON, Vaughn V. SMIDER, Ian WILSON, Michael CRISCITIELLO, Waithaka MWANGI
  • Breaking immunological tolerance with a genetically encoded unnatural amino acid
    Patent number: 8318172
    Abstract: The present invention comprises methods and compositions for producing and/or enhancing an immunological response in a subject against a target moiety such as a disease-related moiety by administration of an antigenic version of the target moiety having one or more unnatural amino acid and/or by administration of an antibody against a version of a target moiety having one or more unnatural amino acid which antibody is cross reactive with the natural target moiety.
    Type: Grant
    Filed: February 7, 2009
    Date of Patent: November 27, 2012
    Assignee: The Scripps Research Institute
    Inventors: Jan Grunewald, Meng-Lin Tsao, Roshan Perera, Richard A. Lerner, Vaughn V. Smider, Peter G. Schultz
  • Breaking Immunological Tolerance with a Genetically Encoded Unnatural Amino Acid
    Publication number: 20110052525
    Abstract: The present invention comprises methods and compositions for producing and/or enhancing an immunological response in a subject against a target moiety such as a disease-related moiety by administration of an antigenic version of the target moiety having one or more unnatural amino acid and/or by administration of an antibody against a version of a target moiety having one or more unnatural amino acid which antibody is cross reactive with the natural target moiety.
    Type: Application
    Filed: February 7, 2009
    Publication date: March 3, 2011
    Applicant: THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Jan Grunewald, Meng-Lin Tsao, Roshan Perera, Richard A. Lerner, Vaughn V. Smider, Peter G. Schultz
  • NON-FLUORESCENT, NON-ENZYMATIC, CHEMILUMINESCENT AQUEOUS ASSAY
    Publication number: 20090298048
    Abstract: This invention provides for nonfluorescent, nonenzymatic, chemiluminescent aqueous assays in which the binding of two ligands is determined by a water soluble label system that emits light upon contact with a chemical energy transferring composition.
    Type: Application
    Filed: November 2, 2004
    Publication date: December 3, 2009
    Applicant: INTEGRIGEN, INC.
    Inventors: Vaughn V. Smider, William Heriot
  • Breaking immunological toterance with a genetically encoded unnatural amino acid
    Publication number: 20090263376
    Abstract: The present invention comprises methods and compositions for producing and/or enhancing an immunological response in a subject against a target moiety such as a disease-related moiety by administration of an antigenic version of the target moiety having one or more unnatural amino acid and/or by administration of an antibody against a version of a target moiety having one or more unnatural amino acid which antibody is cross reactive with the natural target moiety.
    Type: Application
    Filed: February 7, 2009
    Publication date: October 22, 2009
    Applicant: The Scripps Research Institute
    Inventors: Jan Grunewald, Meng-Lin Tsao, Roshan Perera, Richard A. Lerner, Vaughn V. Smider, Peter G. Schultz