Abstract: Systems or techniques that facilitate automated imaging protocol management for hybrid modalities are provided. In various embodiments, a system can electronically access a first medical imaging scanner and a second medical imaging scanner, wherein the first medical imaging scanner and the second medical imaging scanner can be of different image-capture modalities. In various aspects, the system can electronically perform automated imaging protocol management across the first medical imaging scanner and the second medical imaging scanner. In various instances, such automated imaging protocol management can comprise: hybrid-aware scanner registration management; hybrid-aware protocol dependency management; hybrid-aware protocol commit management; hybrid-aware remote protocol marking management; hybrid-aware protocol restore management; hybrid-aware protocol editing management; or hybrid-aware scanner-protocol incompatibility management.