Publication number: 20070167521
Abstract: This invention relates to novel corosolic acid analogs of the formula I, wherein R1, R2, R3, R4 and R5 are as indicated below in each of said analogs: 1. R1=COCH3, R2=R3=R4=H, R5=COOH or R1, =R3=R4=H, R2=COCH3, R5=COOH 2. R1=R2=COCH3, R3=R4=H, R5=COOH 3. R1=COC5H4N, R2=R3=R4=H, R5=COOH 4. R1=COCH2NH2.HC1, R2=R3=R4=H, R5=COOH 5. R1=COCH2(CH3)NH2.HC1, R2=R3=R4=H, R5=COOH 6. R1=COCH:CHC6H2(OCH3)3, R2=R3=R4=H, R5=COOCH3 7. R1 & R2=S02, R3=R4=H, R5=COOH 8. R1=R2=R3=R4=H, R5=CONH2 9. R1=R2=R3=R4=H, R5=CONHC6H5 10. R1=R2=R3=R4=H, R5=CONHCH2CH2NH2 11. R1=R2=R3=R4=H, R5=CON(CH2CH2)2NH 12. R1=R2=R3=R4=H, R5=CONHCH2CH20H 13. R1=R2=R3=R4=H, R5=COOCH3 14. R1=R2=COCH3, R3=R4=H, R5=COOCH3 15. R1=R2=H, R3 & R4=0, R5=COOCH3 16. R1=R2=COCH3, R3 & R4=0, R5=COOCH3 17. R1=R2=H, R3 & R4=0, R5=COOH 18. R1=R2=COCH3, R3 & R4=0, R5=COOH 19. R1 & R2=S02, R3 & R4=0, R5=COOH 20. R1=R2=H, R3 & R4=0, R5=CONH2 21. R1=R2=R3=H, R4=OH, R5=CONH2 22. R1=R2=R3=H, R4=OH, R5=COOCH3 23. R1=R2=R3=R4=H, R5=CH20H 24.
Type:
Application
Filed:
July 8, 2004
Publication date:
July 19, 2007
Inventors:
Ganga Gokaraju, Rama Gokaraju, Venkata Gottumukkala, Trimurtulu Golakoti, Venkateswarlu Somepalli, Venkateswara Chirravuri