Publication number: 20220112212
Abstract: The present invention relates to novel crystalline polymorphs of sodium (4R,12aS)-9-{[(2,4-difluorophenyl) methyl] carbamoyl}-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1?,2?:4,5] pyrazino[2,1-b] [1,3] oxazin-7-olate represented by the following structural formula-1a and process for their preparation. The present invention further relates to novel solvated forms of sodium (4R,12aS)-9-{[(2,4-difluoro phenyl) methyl] carbamoyl}-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1?,2?:4,5] pyrazino[2,1-b][1,3] oxazin-7-olate compound of formula-1a and process for their preparation.
Type:
Application
Filed:
February 4, 2020
Publication date:
April 14, 2022
Applicant:
MSN LABORATORIES PRIVATE LIMITED, R&D CENTER
Inventors:
Thirumalai Rajan SRINIVASAN, Eswaraiah SAJJA, Rajeshwar Reddy SAGYAM, Srinivasulu RAGINENI, Venkata Narasayya SALADI