Patents by Inventor Venkata Vamsi Krishna MALEPATI

Venkata Vamsi Krishna MALEPATI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof
    Patent number: 10729780
    Abstract: The present invention provides methods for preparation of stable multivalent pneumococcal polysaccharide-protein conjugate vaccine formulations. Instant stable formulations show optimal percent adsorption for each conjugate wherein, aggregation can be prevented by employing i) Individual or separate adsorption for conjugates that otherwise show lower percent adsorption by combined adsorption ii) Histidine-Succinic acid buffer system along with shift in pH from neutral pH to acidic pH iii) a polysaccharide to protein ratio between 0.5 to about 1.4 iv) a six-bladed Rushton type turbine impeller in formulation vessels.
    Type: Grant
    Filed: June 3, 2016
    Date of Patent: August 4, 2020
    Assignee: Serum Institute of India Private Ltd.
    Inventors: Rajeev Mhalasakant Dhere, Hitesh Kumar Malviya, Swapan Kumar Jana, Sambhaji Shankar Pisal, Asha Dinesh Mallya, Sunil Mahor, Manish Maheshkumar Gautam, Chetan Vilas Joshi, Venkata Vamsi Krishna Malepati, Prashant Shivaji Jadhav
  • METHODS FOR IMPROVING THE ADSORPTION OF POLYSACCHARIDE-PROTEIN CONJUGATES AND MULTIVALENT VACCINE FORMULATION OBTAINED THEREOF
    Publication number: 20180161445
    Abstract: The present invention provides methods for preparation of stable multivalent pneumococcal polysaccharide-protein conjugate vaccine formulations. Instant stable formulations show optimal percent adsorption for each conjugate wherein, aggregation can be prevented by employing i) Individual or separate adsorption for conjugates that otherwise show lower percent adsorption by combined adsorption ii) Histidine-Succinic acid buffer system along with shift in pH from neutral pH to acidic pH iii) a polysaccharide to protein ratio between 0.5 to about 1.4 iv) a six-bladed Rushton type turbine impeller in formulation vessels.
    Type: Application
    Filed: June 3, 2016
    Publication date: June 14, 2018
    Applicant: Serum Institute of India Privated Ltd.
    Inventors: Rajeev Mhalasakant DHERE, Hitesh Kumar MALVIYA, Swapan Kumar JANA, Sambhaji Shankar PISAL, Asha Dinesh MALLYA, Sunil MAHOR, Manish Maheshkumar GAUTAM, Chetan Vilas JOSHI, Venkata Vamsi Krishna MALEPATI, Prashant Shivaji JADHAV