Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

Abstract: Temperature-controllable reagent cartridges and systems for controlling the temperature in such reagent cartridges are provided. An example such system may include a reagent cartridge having reagent reservoirs located at least in part within an interior plenum volume of a cartridge housing. In such an example system, each reagent reservoir may be defined, in part, by a sidewall, and a first reagent reservoir may be spaced apart from a second reagent reservoir to form a fluid flow passage between corresponding sidewalls thereof. A fluid inlet through the cartridge housing may be provided that fluidically connects the interior plenum volume with a fluid supply port of a temperature control system of an analysis instrument when the reagent cartridge is received by the analysis instrument; a fluid outlet through the cartridge housing that fluidically connects the interior plenum volume with a fluid return port of the temperature control system may also be provided.

Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon. The method also includes detecting optical signals from the sample of the second substrate.

Abstract: Method includes positioning a first carrier assembly on a system stage. The carrier assembly includes a support frame having an inner frame edge that defines a window of the support frame. The first carrier assembly includes a first substrate that is positioned within the window and surrounded by the inner frame edge. The first substrate has a sample thereon. The method includes detecting optical signals from the sample of the first substrate. The method also includes replacing the first carrier assembly on the system stage with a second carrier assembly on the system stage. The second carrier assembly includes the support frame and an adapter plate held by the support frame. The second carrier assembly has a second substrate held by the adapter plate that has a sample thereon.

Abstract: A method of making and using a printer comprising a duplexing unit that pivots along a horizontal plane for media path access. The duplexing unit does not contain any motor driven rollers for moving a media sheet therethrough. The duplexing unit's vertical axis hinge allows the duplexing unit to swing open and closed horizontally.

Abstract: A duplexing unit for reversing an orientation of a sheet in an imaging apparatus, the duplexing unit includes: an outer member including an inner surface; an inner member that is housed within the outer member, the inner member including an outer surface, wherein a duplexing path is provided between the inner surface of the outer member and the outer surface of the inner member, and wherein the inner surface of the outer member has a kinetic coefficient of friction that is between 0.05 and 0.30.

Abstract: A duplexing unit for reversing an orientation of a sheet in an imaging apparatus, the duplexing unit includes an outer member including an inner surface; and an inner member that is housed within the outer member, the inner member including: a stationary structural element having an outer surface with a radius of curvature; and a freely rotatable element having a radius that is larger than the radius of curvature of the stationary structural element, wherein a duplexing path is provided between the inner surface of the outer member and a contact surface of the freely rotatable element.

Abstract: A pivotable duplexing unit is attached to the wall of a printer using a hinge having an axis that is substantially perpendicular to the base. A latch and catch holds the pivotable duplexing unit in a closed position relative to the wall of the printing apparatus. The wall includes a support member for the hinge, and the pivotable duplexing unit further includes a pin for pivoting in a support member of the hinge. The support member includes a bearing surface that is substantially parallel to the base. The pin member includes an end that makes pivotable contact with the bearing surface.

Abstract: A carriage printer includes a printhead; a carriage guide disposed along a carriage scan direction, the carriage guide including a first end and a second end opposite the first end; a carriage for transporting the printhead along the carriage scan direction across the print region, the carriage including a bearing surface that is configured to contact the carriage guide as the carriage transports the printhead; a plurality of carriage guide supports each including a support surface, the plurality of carriage guide supports including a first carriage guide support disposed proximate the first end; a second carriage guide support disposed proximate the second end; and a third carriage guide support disposed between the first carriage guide support and the second carriage guide support; a first biasing force applied in a bias direction proximate the first end; and a second biasing force applied in the bias direction proximate the second end.

Abstract: A carriage printer includes a printhead; a carriage guide disposed along a carriage scan direction, the carriage guide including a first end and a second end opposite the first end; a carriage for transporting the printhead along the carriage scan direction across the print region, the carriage including a bearing surface that is configured to contact the carriage guide as the carriage transports the printhead; a plurality of carriage guide supports each including a support surface, the plurality of carriage guide supports including a first carriage guide support disposed proximate the first end; a second carriage guide support disposed proximate the second end; and a third carriage guide support disposed between the first carriage guide support and the second carriage guide support; a first biasing force applied in a bias direction proximate the first end; and a second biasing force applied in the bias direction proximate the second end.

Abstract: A method of making and using a printer comprising a duplexing unit that pivots along a horizontal plane for media path access. The duplexing unit does not contain any motor driven rollers for moving a media sheet therethrough. The duplexing unit's vertical axis hinge allows the duplexing unit to swing open and closed horizontally.

Abstract: A pivotable duplexing unit is attached to the wall of a printer using a hinge having an axis that is substantially perpendicular to the base. A latch and catch holds the pivotable duplexing unit in a closed position relative to the wall of the printing apparatus. The wall includes a support member for the hinge, and the pivotable duplexing unit further includes a pin for pivoting in a support member of the hinge. The support member includes a bearing surface that is substantially parallel to the base. The pin member includes an end that makes pivotable contact with the bearing surface.