Patents by Inventor Venkateswara Rao Maddamsetty

Venkateswara Rao Maddamsetty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemoenzymatic process for stereoselective preparation of and enatiomers of 2-hydroxy-3-(2-thienyl) propanenitrile
    Patent number: 7045341
    Abstract: A chemoenzymatic process for the stereoselective preparation of both the (R) and (S) enantiomers of 3-hydroxy-3-(2-thienyl) propanenitrile has been developed. These optically pure key intermediates were prepared by enzymatic resolution of (±)3-hydroxy-3-(2-thienyl) propanenitrile both by transesterification and by hydrolysis reaction which were then transformed to both enantiomers of duloxetine.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: May 16, 2006
    Assignee: Council of Scientific and Industrial Research
    Inventors: Ahmed Kamal, Bhasker Ramesh Khanna Gollapalli, Ramu Rondla, Venkateswara Rao Maddamsetty
  • Chemoenzymatic process for stereoselective preparation of R and S enatiomers of 2-hydroxy-3-(2-thienyl) propanenitrile
    Publication number: 20040185540
    Abstract: A chemoenzymatic process for the stereoselective preparation of both the (R) and (S) enantiomers of 3-hydroxy-3-(2-thienyl) propanenitrile has been developed. These optically pure key intermediates were prepared by enzymatic resolution of (+)3-hydroxy-3-(2-thienyl) propanenitrile both by transesterification and by hydrolysis reaction which were then transformed to both enantiomers of duloxetine.
    Type: Application
    Filed: March 20, 2003
    Publication date: September 23, 2004
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Ahmed Kamal, Bhasker Ramesh Khanna Gollapalli, Ramu Rondla, Venkateswara Rao Maddamsetty