Patents by Inventor Venkateswarlu Akella

Venkateswarlu Akella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel anticancer compounds : process for their preparation and pharmaceutical compositions containing them
    Publication number: 20020016363
    Abstract: The present invention relates to novel anticancer agents, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The present invention more particularly relates to novel derivatives of andrographolide, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates. The novel derivatives of andrographolide have the general formula (I).
    Type: Application
    Filed: May 4, 2001
    Publication date: February 7, 2002
    Applicant: DR. REDDY'S RESEARCH FOUNDATION
    Inventors: Srinivas Nanduri, Sairam Pothukuchi, Sriram Rajagopal, Venkateswarlu Akella, Sunilkumar Bhadramma Kochunarayana Pillai, Ranjan Chakrabarti
  • Water soluble analogues of 20(S)-camptothecin
    Patent number: 6214836
    Abstract: Novel water soluble C-ring analogues of 20(S)-camptothecin having the general formula 1. All the compounds of the formula 1 are prepared from the compounds of the general formula 2 having 20(S)-chiral carbon. The compounds of the formula 1 possess potent anti-cancer and anti-viral properties. The invention also provides an alternate process for the preparation of known C-5 substituted compounds of the formula 1.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: April 10, 2001
    Assignees: Dr. Reddy's Research Foundation, Reddy Cheminor, Inc.
    Inventors: Subrahmanyam Duvvuri, Venkateswarlu Akella, Sharma Manohara Vedula, Rao Venkateswara Kalla, Srinivas S.S.V. Akella
  • Water soluble analogues of 20(S)-camptothecin
    Patent number: 6177439
    Abstract: Novel water soluble C-ring analogues of 20(S)-camptothecin having the general formula 1, All the compounds of the formula 1 are prepared from the compounds of the general formula 2 having 20(S)-chiral carbon where R1 to R5 have the meaning given above. The compounds of the formula 1 possess potent anti-cancer and anti-viral properties.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: January 23, 2001
    Assignees: Reddy's Research Foundation, Reddy-Cheminor, Inc.
    Inventors: Subrahmanyam Duvvuri, Venkateswarlu Akella, Sharma Manohara Vedula, Sastry V. R. S. Thungathurthi, Vamsee Krishna Chintakunta, Shobha Madabhushi
  • Water soluble C-ring analogues of 20(S)-camptothecin
    Patent number: 5972955
    Abstract: Novel water soluble C-ring analogs of 20(S)-camptothecin having the formula 1. ##STR1## The compounds of the formula 1 are prepared from the compounds of the formula 12 having C-20(S) chiral carbon. The compounds of the formula 1 possess potent anti-cancer and anti-viral properties.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: October 26, 1999
    Assignee: Dr. Reddy's Research Foundation
    Inventors: Subrahmanyam Duvvuri, Venkateswarlu Akella, Sharma Manohara Vedula, Archana Prabhakar Kulakarni
  • Taxane derivatives from 14-.beta.-hydroxy-10 deacetylbaccatin III
    Patent number: 5763477
    Abstract: Novel taxane derivatives and intermediates having the formula 1. ##STR1## and a process for the preparation of the compounds of the formula 1 from 14-.beta.-hydroxy-10-deacetylbaccatin III of formula 2 ##STR2## and pharmaceutically acceptable compositions containing the taxane derivatives and intermediates of formula 1.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 9, 1998
    Assignee: Dr. Reddy's Research Foundation
    Inventors: Subrahmanyam Duvvuri, Venkateswarlu Akella, Sharma Manohar Vedula, Ramachandra Puranik, Raghavendra Madhva Sattegeri