Patents by Inventor Venumadhav Janganati

Venumadhav Janganati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10428082
    Abstract: The present disclosure relates to triazole derivatives of melampomagnolide B, their synthesis, and their use as anti-cancer compounds.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: October 1, 2019
    Assignees: BioVentures, LLC, The Regents of the University of Colorado, A Body
    Inventors: Venumadhav Janganati, Peter Crooks, Jessica Ponder, Craig Jordan
  • Publication number: 20190040077
    Abstract: The present disclosure relates to triazole derivatives of melampomagnolide B, their synthesis, and their use as anti-cancer compounds.
    Type: Application
    Filed: January 27, 2017
    Publication date: February 7, 2019
    Inventors: Venumadhav Janganati, Peter Crooks, Jessica Ponder, Craig Jordan
  • Patent number: 10118935
    Abstract: The present disclosure provides dimers of melampomagnolide B (MMB), including carbamate, carbonate, succinic amide, ester and carboxamide dimers of MMB. These derivatives are useful for treating cancer in humans, in particular in treating leukemia, including acute myelogenous leukemia (AML).
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: November 6, 2018
    Assignees: BioVentures, LLC, The Regents of the University of Colorado
    Inventors: Venumadhav Janganati, Peter Crooks, Narsimha Reddy Penthala, Craig Jordan, Shobanbabu Bommagani, Jessica Ponder
  • Publication number: 20180237458
    Abstract: The present disclosure provides dimers of melampomagnolide B (MMB), including carbamate, carbonate, succinic amide, ester and carboxamide dimers of MMB. These derivatives are useful for treating cancer in humans, in particular in treating leukemia, including acute myelogenous leukemia (AML).
    Type: Application
    Filed: April 19, 2018
    Publication date: August 23, 2018
    Inventors: Venumadhav Janganati, Peter Crooks, Narsimha Reddy Penthala, Craig Jordan, Shobanbabu Bommagani, Jessica Ponder
  • Patent number: 9981990
    Abstract: The present disclosure provides dimers of melampomagnolide B (MMB), including carbamate, carbonate, succinic amide, ester and carboxamide dimers of MMB. These derivatives are useful for treating cancer in humans, in particular in treating leukemia, including acute myelogenous leukemia (AML). A compound comprising Formula (1) wherein: Z is independently selected from the group consisting of CH2, O, C(O), and CH, wherein when Z is CH, Z is connected to Y via a double bond and Y is N.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: May 29, 2018
    Assignees: BIOVENTURES, LLC, THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Venumadhav Janganati, Peter Crooks, Narsimha Reddy Penthala, Craig Jordan, Shobanbabu Bommagani, Jessica Ponder
  • Patent number: 9920063
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, thiocarbamates, ester and amide derivatives of MMB. These derivatives are useful for treating cancer in humans.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: March 20, 2018
    Assignees: BIOVENTURES, LLC, THE REGENTS OF THE UNIVERSITY OF COLORADO
    Inventors: Shobanbabu Bommagani, Peter Crooks, Narsimha Reddy Penthala, Venumadhav Janganati, Craig T. Jordan, Jessica Ponder
  • Patent number: 9908892
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, and thiocarbamates. The derivatives may be synthesized via an MMB triazole intermediate. These derivatives are useful for treating cancer in humans.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: March 6, 2018
    Assignee: BIOVENTURES, LLC
    Inventors: Venumadhav Janganati, Narsimha Reddy Penthala, Peter A. Crooks, Craig T. Jordan
  • Publication number: 20170362254
    Abstract: The present disclosure provides dimers of melampomagnolide B (MMB), including carbamate, carbonate, succinic amide, ester and carboxamide dimers of MMB. These derivatives are useful for treating cancer in humans, in particular in treating leukemia, including acute myelogenous leukemia (AML). A compound comprising Formula (1) wherein: Z is independently selected from the group consisting of CH2, O, C(O), and CH, wherein when Z is CH, Z is connected to Y via a double bond and Y is N.
    Type: Application
    Filed: December 3, 2015
    Publication date: December 21, 2017
    Inventors: Venumadhav Janganati, Peter Crooks, Narsimha Reddy Penthala, Craig Jordan, Shobanbabu Bommagani, Jessica Ponder
  • Publication number: 20160368929
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, and thiocarbamates. The derivatives may be synthesized via an MMB triazole intermediate. These derivatives are useful for treating cancer in humans.
    Type: Application
    Filed: September 1, 2016
    Publication date: December 22, 2016
    Applicants: The Board of Trustees of the University of Arkansas, University of Rochester
    Inventors: Venumadhav Janganati, Narsimha Reddy Penthala, Peter A. Crooks, Craig T. Jordan
  • Publication number: 20160368928
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, thiocarbamates, ester and amide derivatives of MMB. These derivatives are useful for treating cancer in humans.
    Type: Application
    Filed: August 30, 2016
    Publication date: December 22, 2016
    Inventors: Shobanbabu Bommagani, Peter Crooks, Narsimha Reddy Penthala, Venumadhav Janganati, Craig T. Jordan, Jessica Ponder
  • Patent number: 9487536
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, thiocarbamates, ester and amide derivatives of MMB. These derivatives are useful for treating cancer in humans.
    Type: Grant
    Filed: April 1, 2015
    Date of Patent: November 8, 2016
    Assignees: BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, REGENTS OF THE UNIVERSITY OF COLORADO
    Inventors: Shobanbabu Bommagani, Peter Crooks, Narsimha Reddy Penthala, Venumadhav Janganati, Craig T. Jordan, Jessica Ponder
  • Patent number: 9469650
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, and thiocarbamates. The derivatives may be synthesized via an MMB triazole intermediate. These derivatives are useful for treating cancer in humans.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: October 18, 2016
    Assignees: BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS, UNIVERSITY OF ROCHESTER
    Inventors: Venumadhav Janganati, Narsimha Reddy Penthala, Peter A. Crooks, Craig T. Jordan
  • Publication number: 20160083397
    Abstract: The present invention provides parthenolide derivatives. In particular, the present invention provides parthenolide derivatives that modulate processes controlled by regulated mRNA translation and have anticancer activity.
    Type: Application
    Filed: April 18, 2014
    Publication date: March 24, 2016
    Inventors: Narsimha Reddy Penthala, Peter Crooks, Venumadhav Janganati
  • Publication number: 20160077084
    Abstract: The present invention provides in vivo methods for screening compounds of interest. The methods rely on readily-observable phenotypic changes in amphibian oocytes or early embryos.
    Type: Application
    Filed: April 18, 2014
    Publication date: March 17, 2016
    Inventors: Angus MacNicol, Narsimha Reddy Penthala, Peter Crooks, Venumadhav Janganati
  • Publication number: 20150203508
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, thiocarbamates, ester and amide derivatives of MMB. These derivatives are useful for treating cancer in humans.
    Type: Application
    Filed: April 1, 2015
    Publication date: July 23, 2015
    Inventors: Shobanbabu Bommagani, Peter Crooks, Narsimha Reddy Penthala, Venumadhav Janganati, Craig T. Jordan, Jessica Ponder
  • Publication number: 20150133444
    Abstract: The present disclosure provides derivatives of melampomagnolide B (MMB), including carbonates, carbamates, and thiocarbamates. The derivatives may be synthesized via an MMB triazole intermediate. These derivatives are useful for treating cancer in humans.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Inventors: Venumadhav Janganati, Narsimha Reddy Penthala, Peter A. Crooks, Craig T. Jordan