Patents by Inventor Vera A. Semenova

Vera A. Semenova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9782465
    Abstract: Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus anthracis infection. The recognition of these epitopes correlates with autoimmunity in a subject. Also provided are vaccines that include at least one of these epitopes that when administered to a subject provide improved acquired immunity.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: October 10, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Vera A. Semenova, Pavel Svoboda, Jan Pohl, Conrad P. Quinn
  • Publication number: 20170165344
    Abstract: Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus anthracis infection. The recognition of these epitopes correlates with autoimmunity in a subject. Also provided are vaccines that include at least one of these epitopes that when administered to a subject provide improved acquired immunity.
    Type: Application
    Filed: February 21, 2017
    Publication date: June 15, 2017
    Inventors: Vera A. Semenova, Pavel Svoboda, Jan Pohl, Conrad P. Quinn
  • Patent number: 9610338
    Abstract: Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus anthracis infection. The recognition of these epitopes correlates with autoimmunity in a subject. Also provided are vaccines that include at least one of these epitopes that when administered to a subject provide improved acquired immunity.
    Type: Grant
    Filed: March 26, 2015
    Date of Patent: April 4, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Vera A. Semenova, Conrad P. Quinn, Jan Pohl, Pavel Svoboda
  • Publication number: 20150246108
    Abstract: Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus anthracis infection. The recognition of these epitopes correlates with autoimmunity in a subject. Also provided are vaccines that include at least one of these epitopes that when administered to a subject provide improved acquired immunity.
    Type: Application
    Filed: March 26, 2015
    Publication date: September 3, 2015
    Inventors: Vera A. Semenova, Conrad P. Quinn, Jan Pohl, Pavel Svoboda
  • Patent number: 9102742
    Abstract: Regions of B. anthracis protective antigen are provided representing sequences recognized by antibodies in subjects that have vaccine induced lethal toxin neutralizing anti-PA IgG responses. The recognition of these PA regions enhances the utility of anti-PA IgG reactivity as an immune correlate of protection against anthrax in a subject and increases predictive probability of survival. Also provided are vaccines that include at least one of these PA regions that when administered to a subject improve the predictive value of vaccine induced anti-PA IgG and TNA responses as immune correlates of protection against inhalation anthrax.
    Type: Grant
    Filed: August 27, 2013
    Date of Patent: August 11, 2015
    Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services, Centers for Disease Control and Prevention
    Inventors: Vera A. Semenova, Conrad P. Quinn, Jan Pohl, Pavel Svoboda, Shannon Dalton, Jarad M. Schiffer
  • Patent number: 9046520
    Abstract: Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus anthracis infection. The recognition of these epitopes correlates with autoimmunity in a subject. Also provided are vaccines that include at least one of these epitopes that when administered to a subject provide improved acquired immunity.
    Type: Grant
    Filed: February 10, 2011
    Date of Patent: June 2, 2015
    Assignee: The United States of America, as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention
    Inventors: Vera A. Semenova, Conrad P. Quinn, Jan Pohl, Pavel Svoboda
  • Publication number: 20140004139
    Abstract: Regions of B. anthracis protective antigen are provided representing sequences recognized by antibodies in subjects that have vaccine induced lethal toxin neutralizing anti-PA IgG responses. The recognition of these PA regions enhances the utility of anti-PA IgG reactivity as an immune correlate of protection against anthrax in a subject and increases predictive probability of survival. Also provided are vaccines that include at least one of these PA regions that when administered to a subject improve the predictive value of vaccine induced anti-PA IgG and TNA responses as immune correlates of protection against inhalation anthrax.
    Type: Application
    Filed: August 27, 2013
    Publication date: January 2, 2014
    Applicant: Centers for Disease Control and Prevention
    Inventors: Vera A. Semenova, Conrad P. Quinn, Jan Pohl, Pavel Svoboda, Shannon Dalton, Jarad M. Schiffer
  • Publication number: 20120308597
    Abstract: Regions of Bacillus anthracis protective antigen are provided representing epitopes recognized by antibodies in subjects that have acquired immunity to Bacillus anthracis infection. The recognition of these epitopes correlates with autoimmunity in a subject. Also provided are vaccines that include at least one of these epitopes that when administered to a subject provide improved acquired immunity.
    Type: Application
    Filed: February 10, 2011
    Publication date: December 6, 2012
    Applicant: Centers for Disease Control and Prevention
    Inventors: Vera A. Semenova, Conrad P. Quinn, Jan Pohl, Pavel Svoboda