Abstract: A plaque-inhibiting and/or caries-inhibiting, aqueous composition for use in the oral cavity, such as a toothpaste or mouthwash composition, comprising a water carrier and a therapeutic, effective amount of a perfluoroalkyl surfactant having a perfluoroalkyl group and containing a cationic group, such as a cationic perfluoroalkyl thio ether quaternary tri-methyl ammonium compound or an amphoteric perfluoroalkyl anionic-cationic compound.

Abstract: A plaque-inhibiting and/or caries-inhibiting, aqueous composition for use in the oral cavity, such as a toothpaste or mouthwash composition, comprising a water carrier and a therapeutic, effective amount of a perfluoroalkyl surfactant having a perfluoroalkyl group and containing a cationic group, such as a cationic perfluoroalkyl thio ether quaternary tri-methyl ammonium compound or an amphoteric perfluoroalkyl anionic-cationic compound.

Abstract: A self-gelling aqueous therapeutic composition for topical application and for the sustained release of a medicant compound, which compositions comprise an aqueous ethyl orthosilicate emulsion, a therapeutic compound which is to be released in a sustained manner on topical application, a gelling facilitating agent to aid the in situ gelation of the ethyl orthosilicate composition comprising a surface-active agent and/or a low concentration of an ammonium or fluoride compound and a gelling accelerating compound to accelerate the conversion of the solution to a gel state, which accelerator compound comprises an imidazole compound to effect the self gelling of the composition.

Abstract: A self-gelling composition for topical application, particularly in the oral cavity, which composition comprises: an aqueous solution of ethyl orthosilicate monomer or prepolymer; an active ingredient, such as a fluoride, or an antibiotic for sustained release in the area of topical application; and a gelation agent, to provide, on mixing of the composition, the in situ gelling of the composition within a predetermined time period after topical application, to provide the penetration properties of a low-viscosity solution with the sustained release of the active ingredient from the gel.

Abstract: A self-gelling composition for topical application, particularly in the oral cavity, which composition comprises: an aqueous solution of ethyl orthosilicate monomer or prepolymer; an active ingredient, such as a fluoride, or an antibiotic for sustained release in the area of topical application; and a gelation agent, to provide, on mixing of the composition, the in situ gelling of the composition within a predetermined time period after topical application, to provide the penetration properties of a low-viscosity solution with the sustained release of the active ingredient from the gel.

Abstract: A dental-caries-inhibiting composition, such as toothpaste, mouthwash, or solution for profession application to teeth, which composition comprises a caries-inhibiting amount; for example, 50 to 30000 ppm, of a soluble fluoride and a surfactant having a perfluoroalkyl group in an amount sufficient to increase the formation of fluorapatite from enamel-fluoride interactions.