Patents by Inventor Vera PILS

Vera PILS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS
    Publication number: 20210379087
    Abstract: The invention relates to a composition comprising one or more inhibitors capable of inhibiting at least two of cyclooxygenase-1 (COX-1), cyclooxygenase-2 (COX-2) and lipoxygenase or a composition comprising one or more inhibitors capable of inhibiting an enzyme with arachidonate-Co A ligase activity, specifically long-chain-fatty-acid-Co A ligase (ACSL) 1, ACSL3, ACSL4, ACSL5, ACSL6, SLC27A2 or ACSBG2, or a combination thereof for use in selectively eliminating senescent cells. The invention further relates to an in vitro method of identifying senescent cells in a subject and to a method of identifying candidate compounds for the selective elimination of senescent cells.
    Type: Application
    Filed: October 25, 2019
    Publication date: December 9, 2021
    Inventors: Ingo LÄMMERMANN, Johannes GRILLARI, Vera PILS, Florian GRUBER, Marie-Sophie NARZT