Patents by Inventor Verena Siewers

Verena Siewers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11104907
    Abstract: The invention relates to engineering of acetyl-CoA metabolism in yeast and in particular to production of acetyl-CoA in a non-ethanol producing yeast lacking endogenous gene(s) encoding pyruvate decarboxylase and comprising a heterologous pathway for synthesis of cytosolic acetyl-CoA.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: August 31, 2021
    Assignee: BIOPETROLIA AB
    Inventors: Jens Nielsen, Verena Siewers, Anastasia Krivoruchko, Yiming Zhang, Zongjie Dai
  • Publication number: 20200377894
    Abstract: The invention relates to engineering of acetyl-CoA metabolism in yeast and in particular to production of acetyl-CoA in a non-ethanol producing yeast lacking endogenous gene(s) encoding pyruvate decarboxylase and comprising a heterologous pathway for synthesis of cytosolic acetyl-CoA.
    Type: Application
    Filed: June 12, 2020
    Publication date: December 3, 2020
    Inventors: Jens Nielsen, Verena Siewers, Anastasia Krivoruchko, Yiming Zhang, Zongjie Dai
  • Patent number: 10704050
    Abstract: The invention relates to engineering of acetyl-CoA metabolism in yeast and in particular to production of acetyl-CoA in a non-ethanol producing yeast lacking endogenous gene(s) encoding pyruvate decarboxylase and comprising a heterologous pathway for synthesis of cytosolic acetyl-CoA.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: July 7, 2020
    Assignee: BIOPETROLIA AB
    Inventors: Jens Nielsen, Verena Siewers, Anastasia Krivoruchko, Yiming Zhang, Zongjie Dai
  • Patent number: 10550413
    Abstract: The present invention generally relates to a genetically modified fungal cell capable of producing a very long, chain fatty acid (VLCFA) and/or a VLCFA derivative. The genetically modified fungal cell comprises at least one exogenous gene encoding a fatty acyl-CoA reductase, and at least one gene encoding an elongase, and/or at least one gene encoding a fatty acid synthase.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: February 4, 2020
    Assignee: BIOPETROLIA AB
    Inventors: Florian David, Verena Siewers, Anastasia Krivoruchko, Leonie Wenning, Tao Yu, Yong-Jin Zhou, Jens Nielsen
  • Patent number: 9957513
    Abstract: The present invention relates to the development of genetically engineered yeasts that can produce hydrocarbons in a controllable and economic fashion. More specifically the invention relates to the production of liquid alkanes and alkenes that can be used for liquid transportation fuels, specialty chemicals, or feed stock for further chemical conversion.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: May 1, 2018
    Assignee: BIOPETROLIA AB
    Inventors: Jens Nielsen, Verena Siewers, Paulo Alexandre Goncalves Teixeira, Yongjin Zhou, Nicolaas A. A. Buijs, Florian David
  • Publication number: 20180112240
    Abstract: The present invention generally relates to a genetically modified fungal cell capable of producing a very long, chain fatty acid (VLCFA) and/or a VLCFA derivative. The genetically modified fungal cell comprises at least one exogenous gene encoding a fatty acyl-CoA reductase, and at least one gene encoding an elongase, and/or at least one gene encoding a fatty acid synthase.
    Type: Application
    Filed: April 1, 2016
    Publication date: April 26, 2018
    Inventors: Florian David, Verena Siewers, Anastasia Krivoruchko, Leonie Wenning, Tao Yu, Yong-Jin Zhou, Jens Nielsen
  • Publication number: 20180030460
    Abstract: The present invention relates to the development of genetically engineered yeasts that can produce hydrocarbons in a controllable and economic fashion. More specifically the invention relates to the production of liquid alkanes and alkenes that can be used for liquid transportation fuels, specialty chemicals, or feed stock for further chemical conversion.
    Type: Application
    Filed: August 21, 2017
    Publication date: February 1, 2018
    Inventors: Jens Nielsen, Verena Siewers, Paulo Alexandre Goncalves Teixeira, Yongjin Zhou, Nicolaas A.A. Buijs, Florian David
  • Patent number: 9777283
    Abstract: The present invention relates to the development of genetically engineered yeasts that can produce hydrocarbons in a controllable and economic fashion. More specifically the invention relates to the production of liquid alkanes and alkenes that can be used for liquid transportation fuels, specialty chemicals, or feed stock for further chemical conversion.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: October 3, 2017
    Assignee: Biopetrolia AB
    Inventors: Jens Nielsen, Verena Siewers, Paulo Alexandre Goncalves Teixeira, Yongjin Zhou, Nicolaas A. A. Buijs, Florian David
  • Patent number: 9745602
    Abstract: The present invention relates to the control of gene expression by a heterologous glucose-regulated promoter, to microorganisms in which gene expression is controlled by a heterologous glucose-regulated promoter and to methods using said microorganisms for the production of terpenes during glucose-limited fed-batch fermentation.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: August 29, 2017
    Assignee: FIRMENICH SA
    Inventors: Laurent Daviet, Michel Schalk, Jens Nielsen, Verena Siewers, Christoph Knuf, Gionata Scalcinati
  • Patent number: 9670494
    Abstract: The present invention relates to yeast cells producing high levels of acetoacetyl-CoA. It also relates to a method for making such yeast cells and to the use of such yeast cells in a method for producing acetyl-CoA derived products.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: June 6, 2017
    Assignee: FIRMENICH SA
    Inventors: Jens Nielsen, Verena Siewers, Yun Chen, Laurent Daviet, Michel Schalk
  • Publication number: 20160237444
    Abstract: The present invention relates to the development of genetically engineered yeasts that can produce hydrocarbons in a controllable and economic fashion. More specifically the invention relates to the production of liquid alkanes and alkenes that can be used for liquid transportation fuels, specialty chemicals, or feed stock for further chemical conversion.
    Type: Application
    Filed: October 17, 2014
    Publication date: August 18, 2016
    Applicant: Biopetrolia AB
    Inventors: Jens Nielsen, Verena Siewers, Paulo Alexandre Goncalves Teixeira, Yongjin Zhou, Nicolaas A. A. Buijs, Florian David
  • Publication number: 20160237441
    Abstract: The invention relates to engineering of acetyl-CoA metabolism in yeast and in particular to production of acetyl-CoA in a non-ethanol producing yeast lacking endogenous gene(s) encoding pyruvate decarboxylase and comprising a heterologous pathway for synthesis of cytosolic acetyl-CoA.
    Type: Application
    Filed: October 17, 2014
    Publication date: August 18, 2016
    Inventors: Jens Nielsen, Verena Siewers, Anastasia Krivoruchko, Yiming Zhang, Zongjie Dai
  • Publication number: 20150079646
    Abstract: The present invention relates to yeast cells producing high levels of acetoacetyl-CoA. It also relates to a method for making such yeast cells and to the use of such yeast cells in a method for producing acetyl-CoA derived products.
    Type: Application
    Filed: December 17, 2012
    Publication date: March 19, 2015
    Applicant: FIRMENICH SA
    Inventors: Jens Nielsen, Verena Siewers, Yun Chen, Laurent Daviet, Michel Schalk
  • Publication number: 20140113343
    Abstract: The present invention relates to the control of gene expression by a heterologous glucose-regulated promoter, to microorganisms in which gene expression is controlled by a heterologous glucose-regulated promoter and to methods using said microorganisms for the production of terpenes during glucose-limited fed-batch fermentation.
    Type: Application
    Filed: June 1, 2012
    Publication date: April 24, 2014
    Applicant: FIRMENICH SA
    Inventors: Lauren Daviet, Michel Schalk, Jens Nielsen, Verena Siewers, Christoph Knuf, Gionata Scalcinati