Abstract: A fluid sampling module is provided for utilization in on-line real time fluid monitoring systems. The fluid sampling module can be utilized as a urea input module in a hemodialysis treatment. The hemodialysis monitoring system quantitates the rate and amount of urea removed during the hemodialysis treatment by measuring the urea concentrations as a function of time in the spent dialysate effluent from a hemodialysis machine. The urea input module interfaces with the dialysate effluent waste line from the hemodialysis machine and periodically removes a quantity of the spent dialysate effluent for measurement. The urea input module detects low flow rates and eliminates low flow rate flutter. The urea input module includes a resealable make before break docking interface with the dialysate effluent line and preferably includes a filter between the urea input module and the urea sensor.

Abstract: Authentication and verification of suitability for use of disposable elements can be made by evaluation of characteristic data stored on a non-volatile read/write memory element, especially useful in a photoactivatable agent patient treatment system wherein photoactivatable agents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: A removable U.V. light array assembly for use in a photoactivatable agent, patient treatment system wherein photoactivatable agents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: A removable U.V. light array assembly for use in a photoactivatable agent, patient treatment system wherein photoactivatable agents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: Pump block for interfacing an irradiation chamber with a roller pump in an apparatus for use in a photoactivatable agent, patient treatment system wherein photoactivatable agents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: Automatic operating zero insertion force socket for use in a photoactivatable reagent treatment system wherein photoactivatable agents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: Manually overridable servo controlled valve mechanisms for controlling the flow of fluids through a flexible tube for use in a photoactivatable agent treatment system wherein photoactivatable agents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: Manually overridable servo controlled valve mechanisms for controlling the flow of fluids through a flexible tube for use in a photoactivatable reagent treatment system wherein photoactivatable reagents, in contact with patient blood cells, are irradiated extracorporeally and then retruned to the patient.

Abstract: A blood flow system for processing blood has two phases of operation, an arterial phase and a venous phase. During the arterial phase, the system is filled with blood through operation of an arterial blood pump. When a predetermined blood pressure level in the system has been attained, the arterial blood pump is inactivated and a venous blood pump removes blood from the system for a given number of pump turns. By accurately monitoring both arterial and venous pumps operating cycles, ultrafiltration volume and rate may be determined.

Abstract: Manually overridable servo controlled valve mechanisms for controlling the flow of fluids through a flexible tube for use in a photoactivatable reagent treatment system wherein photoactivatable reagents, in contact with patient blood cells, are irradiated extracorporeally and then returned to the patient.

Abstract: Provided are apparatus and methods of use for extracorporeally treating a patient whereby blood is withdrawn from the patient, separated into a leukocyte enriched portion which, in contact with a photoactivatable reagent, is irradiated and all blood portions being returned to the patient. The preferred apparatus is suitably modified with appropriate tubing sets, valves, pumps, centrifuge and controlling means to perform the patient treatment in three operational phases.

Abstract: Peristaltic pump including a housing having a backing plate and an upstanding arcuate wall, a pump shaft mounted in the backing plate, and a rotatable pump head mounted on the shaft and comprising at least one roller means for squeezing a segment of flexible tubing against the arcuate wall to achieve pumping of a liquid through the tubing. The pump head includes a pivotable handle having a recessed portion which cooperates with a ledge in the pump shaft to prevent the pump head from moving upwardly from the shaft when the pump is in operation. Also included are means comprising a roller bearing and clutch assembly for preventing rotation of the pump head in an incorrect or undesired direction during manual operation.

Abstract: Cassette drawer assembly for receiving an irradiation cassette wherein patient blood is irradiated to photoactivate a reagent in contact therewith, said irradiated blood being returned to the patient as part of the complete treatment.

Abstract: A monitoring arrangement is provided for detecting for extreme pressure conditions in blood tubing lines of a hemodialysis system. The arrangement includes a first pushbutton switch and a pivoted lever arm. A clamping means is located at a first end of the lever arm for clamping the blood tubing line against the first pushbutton switch, and the other end of the lever arm opposes a second pushbutton switch. Under low pressure conditions, the blood pressure in the tubing is no longer sufficient to hold the first pushbutton switch closed. The switch then opens to signal a low pressure condition. Under high pressure conditions, the blood tubing pressure causes the lever arm to pivot so that the far end of the lever activates the second pushbutton switch, which signals a high pressure condition.

Abstract: A two-pump single needle hemodialysis system is provided in which a flexible blood accumulator bag is located between the dialyzer and the second, venous blood pump. The accumulator bag is filled as the first, arterial blood pump is operated. Blood is pumped through the dialyzer and into the bag until the bag is full and taut. At this time, a rise in pressure is detected and the venous blood pump is activated to withdraw blood from the accumulator bag. The use of the accumulator bag assures that low blood pressures are maintained in the system.

Abstract: A blood flow system for processing blood has two phases of operation, an arterial phase and a venous phase. During the arterial phase, the system is filled with blood through operation of an arterial blood pump. When a predetermined blood pressure level in the system has been attained, the arterial blood pump is inactivated and a venous blood pump removes blood from the system for a given number of pump turns.

Abstract: Peristaltic pump including a housing having a backing plate and an upstanding arcuate wall, a pump shaft mounted in the backing plate, and a rotatable pump head mounted on the shaft and comprising at least one roller means for squeezing a segment of flexible tubing against the arcuate wall to achieve pumping of a liquid through the tubing. The pump head includes a pivotable handle having a recessed portion which cooperates with a ledge in the pump shaft to prevent the pump head from moving upwardly from the shaft when the pump is in operation. Also included are means comprising a roller bearing and clutch assembly for preventing rotation of the pump head in an incorrect or undesired direction during manual operation.