Patents by Inventor Veronica Ciolfi

Veronica Ciolfi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FasR antibodies and methods of use
    Patent number: 10053510
    Abstract: Provided herein are an exogenous antibody that binds selectively to a misfolded form of human FasR, and methods and uses for said antibody. Specifically disclosed is the antibody designated AMF 3a-118 which selectively binds the peptide represented by LHHDGQFCH (SEQ ID NO:2) and the antibody designated AMF 3d-19 which selectively binds the peptide represented by NSTVCEH (SEQ ID NO:5).
    Type: Grant
    Filed: May 26, 2014
    Date of Patent: August 21, 2018
    Assignees: PROMIS NEUROSCIENCES INC., THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Marni Diane Uger, Veronica Ciolfi, Neil R. Cashman
  • FasR ANTIBODIES FOR DIAGNOSTIC AND THERAPEUTIC USE
    Publication number: 20160215055
    Abstract: Provided herein are an exogenous antibody that binds selectively to a misfolded form of human FasR, and methods and uses for said antibody. Specifically disclosed is the antibody designated AMF 3a-118 which selectively binds the peptide represented by LHHDGQFCH (SEQ ID NO:2) and the antibody designated AMF 3d-19 which selectively binds the peptide represented by NSTVCEH (SEQ ID NO:5).
    Type: Application
    Filed: May 26, 2014
    Publication date: July 28, 2016
    Inventors: Marni Diane Uger, Veronica Ciolfi, Neil R. Cashman
  • Antibodies and conjugates that target misfolded prion protein
    Patent number: 9296819
    Abstract: Human prion protein, PrP, selectively presents the epitope MDEYSNQNN (SEQ ID No. 14) when PrP misfolds. The misfolded form of human PrP is associated with various disease states. The present invention provides an antibody useful to detect and treat such diseases, including cancer such as ovarian cancer and lymphomas, and transmissible spongiform encephalopathies such as CJD. Also provided is an immunoconjugate in which the antibody is conjugated with urease as cytotoxin.
    Type: Grant
    Filed: June 11, 2013
    Date of Patent: March 29, 2016
    Assignees: ProMIS Neurosciences Inc., Helix BioPharma Corp.
    Inventors: Marni Diane Uger, Viengthong Chai, Veronica Ciolfi, Neil R. Cashman, Baomin Tian, Wah Yau Wong, Heman Lap-Man Chao
  • ANTIBODIES AND CONJUGATES THAT TARGET MISFOLDED PRION PROTEIN
    Publication number: 20150166668
    Abstract: Human prion protein, PrP, selectively presents the epitope MDEYSNQNN (SEQ ID No. 14) when PrP misfolds. The misfolded form of human PrP is associated with various disease states. The present invention provides an antibody useful to detect and treat such diseases, including cancer such as ovarian cancer and lymphomas, and transmissible spongiform encephalopathies such as CJD. Also provided is an immunoconjugate in which the antibody is conjugated with urease as cytotoxin.
    Type: Application
    Filed: June 11, 2013
    Publication date: June 18, 2015
    Inventors: Marni Diane Uger, Viengthong Chai, Veronica Ciolfi, Neil R. Cashman, Baomin Tian, Wah Yau Wong, Heman Lap-Man Chao