Abstract: Recombinant human Erythropoietin is used in a method as a hemostatic agent for the treatment or prevention of bleeding from any organ or body part involved with benign or malignant lesions, surgical traumatic, non-healing/difficult to treat lesions, or radiation injury. The method can control or prevent the bleeding in patients with congenital or acquired disorders of coagulation, platelets, or blood vessels, patients on therapeutic or overdose of anticoagulants or antiplatelet drugs. The method consists of the subcutaneous, intravenous or oral administration of recombinant human Erythropoietin for the purpose of preventing or stopping bleeding.

Abstract: A method for the treatment of diffused GI bleeding by the subcutaneous administration of erythropoietin. The method is suitable for patients with radiation induced proctitis or diffused angiodysplasia of the colon, and makes unnecessary the need for the removal of portions of the GI track. Continuation of the administration of erythropoietin is necessary to avoid subsequent hematochesia and a drop in Hgb/Hcrt. The invention provides a conservative treatment for diffused GI bleeding which works on extensive areas of the GI mucosa. The treatment (1) stops the chronic diffuse GI bleeding, (2) eliminates the need for further transfusions, with its attendant complications (3) treatment is as an outpatient without the need for surgery, (4) the patient is returned to an excellent quality of life, (5) there is a major saving to the health industry, and (6) there are no observed side effects.