Abstract: There is described a method for making an array of micro-needles, comprising the steps of: depositing a plurality of drops of a liquid substance comprising a polymer on a surface of a starting substrate; positioning a pyroelectric substrate at a certain distance from the starting substrate in such a way that the drops deposited are positioned between said surface of the starting substrate and a surface of the pyroelectric substrate; varying the temperature of the pyroelectric substrate or a part thereof to induce on said surface of the pyroelectric substrate a charge density such that starting from the drops deposited, under the effect of an electrodynamic force, respective cones are formed having a tip facing towards the pyroelectric substrate; determining a consolidation of the cones, to form said micro-needles, preventing the tip of said cones from contacting said surfaces of the pyroelectric substrate.

Abstract: There is described a method for making an array of micro-needles, comprising the steps of: depositing a plurality of drops of a liquid substance comprising a polymer on a surface of a starting substrate; positioning a pyroelectric substrate at a certain distance from the starting substrate in such a way that the drops deposited are positioned between said surface of the starting substrate and a surface of the pyroelectric substrate; varying the temperature of the pyroelectric substrate or a part thereof to induce on said surface of the pyroelectric substrate a charge density such that starting from the drops deposited, under the effect of an electrodynamic force, respective cones are formed having a tip facing towards the pyroelectric substrate; determining a consolidation of the cones, to form said micro-needles, preventing the tip of said cones from contacting said surfaces of the pyroelectric substrate.

Abstract: Production and the distribution of pico and nano-drops, which are extracted by the effect of a strong electric field generated by pyroelectric effect, in particular, but not exclusively, from a sessile drop (a drop placed on a surface assumes a form termed “sessile”) or by a liquid film, and distributed on a dielectric substrate. The electric field is advantageously generated applying a heat source on the dielectric substrate or utilizing a laser source emitting in the infrared region. In this new approach, it is not necessary to use fixed electrodes, circuits, high tension generators or to design intentionally, and therefore to realize, pico- and nano-nozzles.

Abstract: The invention concerns a method for the controlled distribution of pico- or nano-volumes of a liquid, comprising the step of: A. Deposing the liquid as a film or separated sessile drops on a surface of a starting substrate; the liquid being extracted and distributed on the surface of a substrate called “destination substrate”, the method being characterized in that: —At least one between said starting substrate and destination substrate is a pyroelectric substrate; The method comprising the following further step: B.