Patents by Inventor Veronique Baudin-Creuza

Veronique Baudin-Creuza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS TO DETERMINE THE QUALITY OF RED BLOOD CELL UNITS
    Publication number: 20230324412
    Abstract: The present invention relates to a method for determining the quality of haemoglobin (Hb) during the storage period of red blood cell (RBC) units comprising a step of detecting soluble alpha-haemoglobin (?-Hb) pool in RBC lysates and concluding that the presence of ?-Hb pool indicates a conservation of quality of Hb during the storage RBCs. Inventors have determined the impact of RBC units aging on the quality of Hb and on the soluble ?-Hb pool level in RBCs. For this purpose, 21 RBC units were collected, stored at +4 to 6° C. and samples were taken at two different storage times (D3-D8 and D38-D42) to evaluate spectral characteristics of Hb and soluble ?-Hb pool in RBCs. Two additional samples were collected from 16 RBC units, at intermediate time points during storage (D13-D17 and D24-D29; n=16). The ?-Hb dosing assay uses the specific character of the interaction between the ?-Hb and the AHSP, the ? chaperone, to trap the ?-Hb present in the RBC lysates of RBC units.
    Type: Application
    Filed: April 8, 2021
    Publication date: October 12, 2023
    Inventors: Véronique BAUDIN-CREUZA, Philippe CHADEBECH, Corinne VASSEUR, France PIRENNE
  • Method for diagnosing a hemoglobin-related disorder
    Patent number: 9494603
    Abstract: The invention relates to a method for diagnosing, staging and/or monitoring a hemoglobin-related disorder such as ?-thalassemia or a treatment against said hemoglobin-related disorder in a subject in need thereof based on the detection and/or quantification the presence of free ?-Hb pool in a biological sample obtained from said subject.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: November 15, 2016
    Assignees: Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris-Sud, Assistance Publique—Hopitaux de Paris, Universite Paris Est Creteil Val de Marne
    Inventors: Veronique Baudin-Creuza, Corinne Vasseur, Frederic Galacteros
  • Method for Diagnosing a Hemoglobin-Related Disorder
    Publication number: 20150293126
    Abstract: The invention relates to a method for diagnosing, staging and/or monitoring a hemoglobin-related disorder such as ?-thalassemia or a treatment against said hemoglobin-related disorder in a subject in need thereof based on the detection and/or quantification the presence of free ?-Hb pool in a biological sample obtained from said subject.
    Type: Application
    Filed: June 24, 2015
    Publication date: October 15, 2015
    Applicants: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Paris-Sud, Assistance Publique - Hopitaux de Paris, Universite Paris Est Creteil Val de Marne
    Inventors: Veronique Baudin-Creuza, Corinne Vasseur, Frederic Galacteros
  • Method for diagnosing a hemoglobin-related disorder
    Patent number: 9097728
    Abstract: A method for diagnosing and/or staging a hemoglobin disorder such as ?-thalassemia involves contacting a blood sample of a subject with an Alpha-Hemoglobin Stabilizing Protein which may be present on a solid support, and detecting and/or quantifying free ?-Hb. Detection or quantification can be achieved by photometry such as HTRF or immunological procedures such as EIA and ELISA. The free ?-Hb is compared to a reference value, and can be used to correlate with the diagnosis and/or staging of the hemoglobin disorder for the subject.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: August 4, 2015
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Universite Paris-Sud, Assistance Publique-Hopitaux de Paris, Universite Paris Est Creteil Val de Marne
    Inventors: Veronique Baudin-Creuza, Corinne Vasseur, Frederic Galacteros
  • METHOD FOR DIAGNOSING A HEMOGLOBIN-RELATED DISORDER
    Publication number: 20120052516
    Abstract: The invention relates to a method for diagnosing, staging and/or monitoring a hemoglobin-related disorder such as ?-thalassemia or a treatment against said hemoglobin-related disorder in a subject in need thereof based on the detection and/or quantification the presence of free ?-Hb pool in a biological sample obtained from said subject.
    Type: Application
    Filed: April 23, 2010
    Publication date: March 1, 2012
    Inventors: Veronique Baudin-Creuza, Corinne Vasseur, Frederic Galacteros