Abstract: The present invention relates to the medical field. In a first aspect the present invention relates to novel water soluble cyclodextrin-curcumin complexes having a pharmacological activity, in particular an anti-tumor and/or anti-inflammatory activity, and improved physico-chemical properties. In a second aspect, the present invention relates to a method for preparation of said water soluble curcumin derivatives. The invention further relates in a third aspect to a pharmaceutical composition comprising an effective amount of said water soluble curcumin derivatives. In a fourth aspect, the present invention concerns the use of said water soluble cucumin derivatives as a medicament and the use of said water soluble curcumin derivatives for the preparation of a medicament for the treatment of cancer and inflammatory diseases.

Abstract: The present invention relates to a host material comprising a compound having two carbazole moieties which is suitable for blue-emitting OLEDs. Surprisingly, it has been found that when appropriate substituents are present in the carbazole structure, the solubility of the compounds can be improved without any adverse effect on the OLED performance. The present invention further relates to the use of the host materials and to an organic light emitting device comprising the host material.

Abstract: The present invention relates to the biology and mechanism of action of the naturally occurring compound Narciclasine, especially as an anti-cancer agent for brain tumors. The invention provides new insights on the target molecule of Amaryllidaceae isocarbostyril derivatives as for example Narciclasine and provides new prodrugs of these Amaryllidceae isocabostyril constituents for treating cancer, specifically cancers or tumors located in the brain.

Abstract: The present invention relates to a host material comprising a compound having a carbazole moiety which is suitable for blue-emitting OLEDs. Surprisingly, it has been found that when appropriate substituents are present in the carbazole structure, the solubility of the compounds can be improved without any adverse effect on the OLED performance. The present invention further relates to the use of the host materials and to an organic light emitting device comprising the host material.

Abstract: The present invention relates to the medical field. In a first aspect the present invention relates to novel water soluble cyclodextrin-curcumin complexes having a pharmacological activity, in particular an anti-tumour and/or anti-inflammatory activity, and improved physico-chemical properties. In a second aspect, the present invention relates to a method for preparation of said water soluble curcumin derivatives. The invention further relates in a third aspect to a pharmaceutical composition comprising an effective amount of said water soluble curcumin derivatives. In a fourth aspect, the present invention concerns the use of said water soluble cucumin derivatives as a medicament and the use of said water soluble curcumin derivatives for the preparation of a medicament for the treatment of cancer and inflammatory diseases.

Abstract: The present invention relates to a host material comprising a compound having two carbazole moieties which is suitable for blue-emitting OLEDs. Surprisingly, it has been found that when appropriate substituents are present in the carbazole structure, the solubility of the compounds can be improved without any adverse effect on the OLED performance. The present invention further relates to the use of the host materials and to an organic light emitting device comprising the host material.

Abstract: A telomerisation process is described whereby haloalkanes like tetrachloromethane are added to halogenated olefins like 2-chloroprop-1-ene in the presence of an iron catalyst and a phosphite. The reaction products, e.g. 1,1,1,3,3-pentachlorobutane, can be fluorinated.

Abstract: A process for the production of a fluorine containing ?-hydroxy carboxylic acid by hydrolyzing a fluorine containing ?-hydroxy nitrite in the presence of a nitrilase.

Abstract: A telomerisation process is described whereby haloalkanes like tetrachloromethane are added to halogenated olefins like 2-chloroprop-1-ene in the presence of an iron catalyst and a phosphite. The reaction products, e.g. 1,1,1,3,3-pentachlorobutane, can be fluorinated.

Abstract: The present invention relates to a fluorination method for the synthesis of halofluoroorganic compounds which can be used, inter alia, as precursors in the synthesis of 2,3-unsaturated fluoroorganic carbonyl compounds comprising a fluorine substituent in the 2 position.

Abstract: Method of manufacture of a hydrofluoroalkane comprising the use of a Lewis base as stabilizer of the hydrofluoroalkane. No drawings.

Abstract: Process for manufacturing an organic compound comprising at least one oxygenated functional group, according to which an organic precursor comprising an oxidizable functionality is subjected to a reaction with an imidoaromatic percarboxylic acid.

Abstract: Process for the preparation of a halogenated olefin by reaction of an alkyne and/or of an allene compound with a hydrogen halide in a liquid medium comprising at least one hydrohalogenation catalyst comprising at least one palladium compound.

Abstract: Method of manufacture of a hydrofluoroalkane comprising the use of a Lewis base as stabilizer of the hydrofluoroalkane. No drawings.

Abstract: Process for the manufacture of 1,1,1-trifluoroethane (HFC-143a), according to which 1,1-difluoro-1-chloroethane (HCFC-142b) is subjected to a vapour-phase reaction with hydrogen fluoride (HF) in the presence of a hydrofluorination catalyst, in which process the molar ratio of the HCFC-142b introduced to the HF introduced into the vapour-phase reaction is greater than or equal to 1 and less than 1.3.

Abstract: Process for preparing SO2F2 according to which SO2ClF is introduced into a gas-phase reaction step with hydrogen fluoride.

Abstract: Method of manufacture of a hydrofluoroalkane comprising the use of a Lewis base as stabilizer of the hydrofluoroalkane.

Abstract: Process for the preparation of a halogenated olefin Process for the preparation of a halogenated olefin by reaction of an alkyne and/or of an allene compound with a hydrogen halide in a liquid medium comprising at least one hydrohalogenation catalyst comprising at least one palladium compound.

Abstract: The present invention relates to a fluorination method for the synthesis of halofluoroorganic compounds which can be used, inter alia, as precursors in the synthesis of 2,3-unsaturated fluoroorganic carbonyl compounds comprising a fluorine substituent in the 2 position.

Abstract: Process for preparing halogenated hydrocarbons, comprising at least 3 carbon atoms, by catalytic telomerization between a haloalkane and an olefin in the presence of an amine with a high boiling point as co-catalyst. 1,1,1,3,3-Pentachloropropane and 1,1,1,3,3-pentachlorobutane are thus prepared under mild conditions in good yield and the catalyst/co-catalyst system can be easily separated by distillation and recycled.