Patents by Inventor Vesna D. Garovic

Vesna D. Garovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240016804
    Abstract: This document relates to methods and materials for assessing and/or treating hypertensive disorders of pregnancy (e.g., preeclampsia) and/or one or more comorbidities associated with a hypertensive disorder of pregnancy. For example, methods and materials for determining if a female mammal has, or is likely to develop, a hypertensive disorder of pregnancy are provided. In addition, methods for using one or more senotherapeutic agents to treat a female mammal having, or at risk of developing, a hypertensive disorder of pregnancy (e.g., preeclampsia) are provided.
    Type: Application
    Filed: August 14, 2020
    Publication date: January 18, 2024
    Inventors: Vesna D. Garovic, Tamar Tchkonia, James L. Kirkland
  • Patent number: 10336822
    Abstract: This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: July 2, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Publication number: 20180246115
    Abstract: This document provides methods and materials related to high-throughput early detection of or point-of-care early detection of pregnant women susceptible to developing preeclampsia. For example, methods and materials related to performing flow cytometry or an ELISA to detect an elevated level of urinary podocytes within a urine sample of a pregnant woman early during her pregnancy to identify her as being susceptible to developing preeclampsia later during her pregnancy are provided. In addition, methods and materials related to performing flow cytometry or an ELISA to detect a lack of an elevated level of urinary podocytes within a urine sample of a pregnant woman early during her pregnancy to identify her as not being susceptible to developing preeclampsia later during her pregnancy are provided.
    Type: Application
    Filed: February 26, 2018
    Publication date: August 30, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Publication number: 20180002416
    Abstract: This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided.
    Type: Application
    Filed: September 13, 2017
    Publication date: January 4, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Patent number: 9810695
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Grant
    Filed: January 17, 2017
    Date of Patent: November 7, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Patent number: 9765137
    Abstract: This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: September 19, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Publication number: 20170122960
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Application
    Filed: January 17, 2017
    Publication date: May 4, 2017
    Inventor: Vesna D. Garovic
  • Patent number: 9557342
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: January 31, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Publication number: 20170003299
    Abstract: This document provides methods and materials involved in determining whether or not a mammal with diabetic nephropathy or glomerulonephritis is undergoing podocyte injury. For example, methods and materials related to the use of urinary microvesicles to determine whether or not a mammal with diabetic nephropathy or glomerulonephritis is undergoing podocyte injury are provided.
    Type: Application
    Filed: November 5, 2014
    Publication date: January 5, 2017
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Vesna D. Garovic, Muthuvel Jayachandran
  • Publication number: 20160060333
    Abstract: This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided.
    Type: Application
    Filed: November 9, 2015
    Publication date: March 3, 2016
    Inventor: Vesna D. Garovic
  • Patent number: 9213038
    Abstract: This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: December 15, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Publication number: 20150268253
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Application
    Filed: June 8, 2015
    Publication date: September 24, 2015
    Inventor: Vesna D. Garovic
  • Publication number: 20150168418
    Abstract: This document provides methods and materials related to high-throughput early detection of or point-of-care early detection of pregnant women susceptible to developing preeclampsia. For example, methods and materials related to performing flow cytometry or an ELISA to detect an elevated level of urinary podocytes within a urine sample of a pregnant woman early during her pregnancy to identify her as being susceptible to developing preeclampsia later during her pregnancy are provided. In addition, methods and materials related to performing flow cytometry or an ELISA to detect a lack of an elevated level of urinary podocytes within a urine sample of a pregnant woman early during her pregnancy to identify her as not being susceptible to developing preeclampsia later during her pregnancy are provided.
    Type: Application
    Filed: May 31, 2013
    Publication date: June 18, 2015
    Inventor: Vesna D. Garovic
  • Publication number: 20140322721
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Application
    Filed: June 6, 2014
    Publication date: October 30, 2014
    Inventor: Vesna D. Garovic
  • Publication number: 20140302538
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Application
    Filed: June 24, 2014
    Publication date: October 9, 2014
    Inventor: Vesna D. Garovic
  • Publication number: 20140051185
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Application
    Filed: September 20, 2013
    Publication date: February 20, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Publication number: 20140030743
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Application
    Filed: September 6, 2013
    Publication date: January 30, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Vesna D. Garovic
  • Publication number: 20130296397
    Abstract: This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided.
    Type: Application
    Filed: May 20, 2013
    Publication date: November 7, 2013
    Inventor: Vesna D. Garovic
  • Publication number: 20130034861
    Abstract: This document provides methods and materials related to determining whether or not a human receiving a therapy (e.g., an anti-VEGF therapy such as a bevacizumab therapy) has developed or is at risk for developing proteinuria. For example, methods and materials for detecting urinary podocytes to determine whether or not a human receiving anti-VEGF therapy has or is at risk for developing proteinuria or kidney injury are provided.
    Type: Application
    Filed: December 21, 2010
    Publication date: February 7, 2013
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventor: Vesna D. Garovic
  • Publication number: 20090104649
    Abstract: This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided.
    Type: Application
    Filed: November 19, 2008
    Publication date: April 23, 2009
    Inventor: Vesna D. Garovic