Abstract: Methods and systems are provided for performing cathode calibration in a detector assembly. In one embodiment, a method comprises adjusting a cathode bias of a detector based on a total number of events occurring in the detector during a time period while maintaining an anode bias at a desired value, the events corresponding to photon energy detected by the detector. In this way, an automated cathode calibration procedure may be applied to calibrate the detector assembly.

Abstract: Methods and systems are provided for performing cathode calibration in a detector assembly. In one embodiment, a method comprises adjusting a cathode bias of a detector based on a total number of events occurring in the detector during a time period while maintaining an anode bias at a desired value, the events corresponding to photon energy detected by the detector. In this way, an automated cathode calibration procedure may be applied to calibrate the detector assembly.

Abstract: An imaging system includes a first silicon photomultiplier (SiPM) comprising an array of microcells. Each microcell is an avalanche photodiode (APD) operated in a Geiger mode, a first area of the first SiPM, comprising at least one of the microcells, is electrically isolated from all other microcells, and a signal from the first area, resulting from at least one photon pulse, is used to determine a gain of the first SiPM.

Abstract: An imaging system includes a first silicon photomultiplier (SiPM) comprising an array of microcells. Each microcell is an avalanche photodiode (APD) operated in a Geiger mode, a first area of the first SiPM, comprising at least one of the microcells, is electrically isolated from all other microcells, and a signal from the first area, resulting from at least one photon pulse, is used to determine a gain of the first SiPM.

Abstract: A method for gain calibration of a gamma ray detector includes measuring signals generated by one or more light sensors of a gamma ray detector, generating one or more derived curves using the measured signals as a function of bias voltage and identifying a transition point in the one or more derived curves. The method also includes determining a breakdown voltage of the one or more light sensors using the identified transition point and setting a bias of the one or more light sensors based on the determined breakdown voltage.

Abstract: Methods and systems for gain calibration of a gamma ray detector are provided. One method includes measuring signals generated by one or more light sensors of a gamma ray detector, generating one or more derived curves using the measured signals as a function of bias voltage and identifying a transition point in the one or more derived curves. The method also includes determining a breakdown voltage of the one or more light sensors using the identified transition point and setting a bias of the one or more light sensors based on the determined breakdown voltage.

Abstract: A method for calibrating multi-headed high sensitivity and high spatial resolution dynamic imaging systems, especially those useful in the acquisition of tomographic images of small animals. The method of the present invention comprises: simultaneously calibrating two or more detectors to the same coordinate system; and functionally correcting for unwanted detector movement due to gantry flexing.