Abstract: One or more systems, devices, computer program products and/or computer-implemented methods of use provided herein relate to teleconferencing and, more specifically, to the gathering and conveying of information over a teleconference by a digital delegate. A computer-implemented system can comprise a memory that can store computer executable components. The computer-implemented system can further comprise a processor that can execute the computer executable components stored in the memory, wherein the computer executable components can comprise a digital delegate component that accesses a teleconference via a computer application as a teleconference participant and an analysis component that analyzes teleconference monitoring information of the teleconference to determine responses to one or more defined points of interest determined by a meeting invitee.

Abstract: A retractable step and side bar assembly that can be used for raised vehicles, such as trucks. The retractable step can be configured to provide for significant reach in a deployed position to allow for a user to enter the raised vehicle. Further, in the stowed position the retractable step can be located within the side bar, thereby providing a low profile as well as an enhanced aesthetic appearance.

Abstract: An embodiment records execution of a workflow comprising a skill, the recording generating workflow data. An embodiment selects, using the workflow data, an ontology tree having above a threshold amount of similarity to the workflow. An embodiment constructs, using the ontology tree and the workflow data, a first skill tree corresponding to the workflow. An embodiment integrates, into an existing skill tree of an application, the first skill tree, the integrating resulting in an integrated skill tree of the application. An embodiment executes, responsive to an intent requesting execution of the skill using new data, using the integrated skill tree and the new data, the skill.

Abstract: The present invention relates to a combination therapy a CHEK1 inhibitor and a TOP1 inhibitor for use in a method of treatment of colorectal cancer in a patient.

Abstract: Conditioning prompts for generative artificial intelligence (AI) systems includes receiving a user prompt via a user interface. The user prompt is for a generative artificial intelligence system and is specified as natural language. A selected prompt class is chosen from a plurality of prompt classes by matching a natural language processing analysis of the user prompt to a prompt template of the selected prompt class. A well-structured prompt is created by transforming the user prompt based on the prompt template of the selected prompt class. A conditioned prompt is generated by combining a set of one or more conditioning instructions from the selected prompt class with the well-structured prompt. The conditioned prompt is submitted to the generative artificial intelligence system. The conditioned prompt is configured to evoke a response including a structured output from the generative artificial intelligence system.

Abstract: Described herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.

Abstract: Systems and methods are provided for replacing a first server of a first node a computer network by adding a second server configured with a database system as a second node to the computer network. A snapshot of a first database of database files that is communicatively coupled to the first node may be taken. The snapshot may be applied to the second server by attaching the snapshot of the first database as a second database to the second server and configuring the second server to match the first server. A failover of the computer network to the second node with the second server having the second database attached may be forced. Voting may be switched to the second server of the second node of the computer network and the first node of the computer network may be removed when the forced failover is successful.

Abstract: A recording of a call is authenticated using a distributed transaction ledger. A call between two or more participants is recorded to generate a call recording. A record of the call recording is stored within a distributed transaction ledger. At a later time, such as in response to an access request for auditing or an authentication request, the call recording is authenticated based on information associated with the record within the distributed transaction ledger. An indication of the authentication is then output, such as for further processing or display.

Abstract: The present invention relates to a method of obtaining an image of a biological sample in a cuvette.

Abstract: Audio qualities of a call and of a call recording are identified and compared to authenticate the call recording as a true representation of the call. A call is enabled between two or more participants, and the call is recorded to generate a call recording. The call recording is authenticated based on a match between audio watermarks included within the call and audio watermarks included within the call recording. An indication of the authentication is then output, such as for further processing or display.

Abstract: The present invention relates a method for creating organoids, each simulating a biological organ having an organ development state. A substrate is provided, which has a plurality of cavities, each cavity being designed, in its size and form, to receive the organ to be simulated having the organ development state to be achieved. The cavities each have the form of a recess. The recesses have a length and a width, the length being greater than the width. Microfilaments are provided, each having a length which is greater than the width of the recesses and less than the length of the recesses. The individual microfilaments are arranged in the cavities. Living culturable cells are also arranged in the cavities. Conditions provided in the cavities for the culture of the cells on the individual microfilaments. The invention relates to a cell culture and a device for producing an arrangement for creating organoids.

Abstract: A method of characterizing a device under test (DUT) includes illuminating the DUT with a broadband optical beam within an optical field of view (FOV), illuminating the DUT with an X-ray beam within an X-ray FOV overlapping the optical FOV, and concurrently acquiring X-ray metrology information, e.g., one or more X-ray images utilizing various modalities, such as absorption, phase contrast difference, darkfield, small angle X-ray scattering (SAXS) and/or fluorescence, from the X-ray FOV and a plurality of optical images of the optical FOV, each of the optical images corresponding to respective selected wavelengths of the broadband optical beam from each of ultraviolet, visible, and infrared wavelengths, for example including deep ultraviolet, near infrared, or short-wavelength infrared wavelengths. The DUT may be one or more substrates, e.g., stacked, and include electronic devices such as three-dimensional integrated devices.

Abstract: Upper body garments (10) (e.g., jackets, vests or the like) are provided having front (12) and back panels enclosing a torso region of a wearer. The back panel includes a cushion back panel (14) having an upper end attached to the front panel (12) at shoulder regions of the garment (10) and extending from the upper end thereof to a lower end positioned at or below a waist region of the wearer. A pull cord (50, 52) has one end operably connected to the lower end of the cushion back panel (14) and an opposite free end positioned near one of the shoulder regions of the garment (10) such that a pull force exerted on the latter when the cushion back panel (14) is in an unattached configuration causes the cushion back panel (14) to roll onto itself from the lower end thereof toward the upper end thereof and thereby form a cushion roll (60) at a neck region of the wearer.

Abstract: A tissue lumen stent is provided with a body having an elongated tubular configuration and a foreshortened configuration. In the foreshortened configuration, downstream and upstream ends of the body expand radially into downstream and upstream flange structures, leaving a generally cylindrical saddle region therebetween. In some embodiments, the flange structures are non-symmetrical with respect to one another. Systems and methods of using the stents are also disclosed.

Abstract: The present invention relates to a combination therapy of an IGF1R inhibitor together with an Akt inhibitor for the treatment of cancer, such as colorectal cancer, ovarian cancer, and endometrial cancer.

Abstract: A method of preparing an acryloxy-functional organosilicon compound is provided. The method comprises reacting (A) an initial organosilicon compound and (B) an acrylate compound in the presence of (C) a catalyst. The initial organosilicon compound (A) has one alcohol functional group (i.e., is monohydroxyl functional). The catalyst (C) has the formula M[RC(O)CHC(O)R]4, where M is a group IV transition metal and each R is an independently selected substituted or unsubstituted hydrocarbyl group. An acryloxy-functional organosilicon compound prepared by the method is also provided. The acryloxy-functional organosilicon compound is prepared in increased purity, without relying on toxic catalysts.

Abstract: A user experience workflow may be configured based on input received for various object types selectively arranged within the user experience workflow and then bound to a destination identifier, such as a telephone number or web address. A user interface of software for configuring a user experience workflow is presented at a user device and input from that user device is used to selectively arrange objects within a user experience workflow and/or to configure objects thereof. After configurations are applied to the objects, the user experience workflow is bound to the destination identifier. An end user device which accesses the destination identifier (e.g., by calling the telephone number, visiting the web address, or using an application connecting to the web address) may then traverse the user experience workflow, including in some cases having configured content presented thereto.