Patents by Inventor Vibeke Mindahl Rafa

Vibeke Mindahl Rafa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIGEN PRESENTING SCAFFOLDS FOR IMMUNE-CELL MANIPULATION
    Publication number: 20230310562
    Abstract: The present invention relates to artificial antigen presenting cell (aAPC) scaffolds to provide cells with specific functional stimulation to obtain phenotypic and functional properties ideal to mediate tumor regression or viral clearance. In particular, the scaffolds of the present invention comprise antigens, such as peptide-MHC (pMHC) class I molecules, and specific combinations of cytokines and co-stimulatory molecules to allow effective expansion and functional stimulation of specific T cells.
    Type: Application
    Filed: December 9, 2022
    Publication date: October 5, 2023
    Inventors: Sine Reker Hadrup, Vibeke Mindahl Rafa, Søren Nyboe Jakobsen
  • Antigen presenting scaffolds for immune-cell manipulation
    Patent number: 11590214
    Abstract: The present invention relates to artificial antigen presenting cell (aAPC) scaffolds to provide cells with specific functional stimulation to obtain phenotypic and functional properties ideal to mediate tumor regression or viral clearance. In particular, the scaffolds of the present invention comprise antigens, such as peptide-MHC (pMHC) class I molecules, and specific combinations of cytokines and co-stimulatory molecules to allow effective expansion and functional stimulation of specific T cells.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: February 28, 2023
    Assignee: Danmarks Tekniskte Universitet
    Inventors: Sine Reker Hadrup, Vibeke Mindahl Rafa, Søren Nyboe Jakobsen
  • ANTIGEN PRESENTING SCAFFOLDS FOR IMMUNE-CELL MANIPULATION
    Publication number: 20190316069
    Abstract: The present invention relates to artificial antigen presenting cell (aAPC) scaffolds to provide cells with specific functional stimulation to obtain phenotypic and functional properties ideal to mediate tumor regression or viral clearance. In particular, the scaffolds of the present invention comprise antigens, such as peptide-MHC (pMHC) class I molecules, and specific combinations of cytokines and co-stimulatory molecules to allow effective expansion and functional stimulation of specific T cells.
    Type: Application
    Filed: December 20, 2017
    Publication date: October 17, 2019
    Inventors: Sine Reker Hadrup, Vibeke Mindahl Rafa, Søren Nyboe Jakobsen