Patents by Inventor Vicki E. Kelley

Vicki E. Kelley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Induction of tolerance to a foreign antigen IL-2 receptor-binding substances
    Patent number: 5152980
    Abstract: A method of inducing tolerance to a foreign antigen in a mammal, by administering an IL-2-receptor-positive-cell-destroying amount of a substance capable of destroying IL-2-receptor-positive cells which are newly activated in response to the antigen, to a degree which supresses the mammal's humoral immune response to a subsequent challenge with the antigen.
    Type: Grant
    Filed: May 18, 1989
    Date of Patent: October 6, 1992
    Assignees: The Beth Israel Hospital Association, Brigham and Women's Hospital
    Inventors: Terry B. Strom, Vicki E. Kelley
  • Composition having reduced nephrotoxocity comprising a fatty acid containing component and cyclosporine
    Patent number: 5118493
    Abstract: Compositions comprising cyclosporine in combination with a vehicle comprising a fatty acid component comprising a fatty acid of the omega-3 or a pharmacologically acceptable salt thereof. Methods for mediating the nephrotoxic effect of cyclosporine and for reducing cyclosporine induced renal prostaglandins comprising administering said cyclosporine in combination with said fatty acid component or a pharmacologically acceptable salt thereof. Eicosapentaenoic acid and docosahexanoic acid are preferred omega-3 fatty acids of the present invention. The compositions and methods of the present invention are useful in clinical and preclinical therapeutic cyclosporine treatment of animals, including humans.
    Type: Grant
    Filed: January 11, 1991
    Date of Patent: June 2, 1992
    Assignees: Brigham and Women's Hospital, Oregon Health Sciences University
    Inventors: Vicki E. Kelley, William M. Bennett