Patents by Inventor Vicki Rosen

Vicki Rosen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BMP-6 proteins
    Patent number: 6207813
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: November 9, 1998
    Date of Patent: March 27, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • BMP-3 products
    Patent number: 6177406
    Abstract: Purified BMP-3 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: January 23, 2001
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki Rosen
  • BMP products
    Patent number: 6150328
    Abstract: Purified BMP-2 and BMP-4 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 14, 1991
    Date of Patent: November 21, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki A. Rosen
  • BMP-9 compositions
    Patent number: 6034061
    Abstract: Purified Bone Morphogenetic Protein (BMP)-9 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair, and in hepatic growth and function.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: March 7, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Vicki A. Rosen, John M. Wozney, Anthony J. Celeste, Scott R. Thies, Jeffrey R. Song
  • BMP-12 and BMP-13 proteins and DNA encoding them
    Patent number: 6027919
    Abstract: The present invention relates to a novel family of purified proteins, and compositions containing such proteins, which compositions are useful for the induction of tendon/ligament-like tissue formation, wound healing and ligament and other tissue repair. The present invention further relates to DNA molecules, vectors and host cells useful for production of such proteins.
    Type: Grant
    Filed: November 2, 1994
    Date of Patent: February 22, 2000
    Assignee: Genetics Institute, Inc.
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Methods of administering BMP-5 compositions
    Patent number: 5939388
    Abstract: Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: August 17, 1999
    Inventors: Vicki A. Rosen, John M. Wozney, Elizabeth A. Wang
  • Cartilage induction by bone morphogenetic proteins
    Patent number: 5902785
    Abstract: Compositions of proteins with cartilaginous tissue inducing and maintenance activity are disclosed. The compositions are useful in the treatment of osteoarthritis, cartilage defects and in related tissue repair.
    Type: Grant
    Filed: May 7, 1996
    Date of Patent: May 11, 1999
    Assignee: Genetics Institute, Inc.
    Inventors: Gary Hattersley, Neil M. Wolfman, Elisabeth A. Morris, Vicki A. Rosen
  • Bone morphogenetic protein (BMP)--6
    Patent number: 5849880
    Abstract: Purified bone morphogenetic protein (BMP)-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 15, 1998
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide and methods of inducing cartilage by administration of same
    Patent number: 5846931
    Abstract: Compositions of proteins with chondrocyte and cartilaginous tissue inducing activity, as well as method of using those compositions, are disclosed. The compositions comprise one or more proteins of the transforming growth factor-.beta. (TGF-.beta.) superfamily of proteins, particularly bone morphogenetic proteins (BMPs), in combination with parathyroid hormone related polypeptide (PTHrP) or an equivalent PTH-like polypeptide. The compositions and methods are useful in the treatment of osteoarthritis, cartilage defects and in related tissue repair.
    Type: Grant
    Filed: September 10, 1997
    Date of Patent: December 8, 1998
    Inventors: Gary Hattersley, Vicki A. Rosen
  • Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
    Patent number: 5700774
    Abstract: Compositions of proteins with chondrocyte and cartilaginous tissue inducing activity, as well as method of using those compositions, are disclosed. The compositions comprise one or more proteins of the transforming growth factor-.beta. (TGF-.beta.) superfamily of proteins, particularly bone morphogenetic proteins (BMPs), in combination with parathyroid hormone related polypeptide (PTHrP) or an equivalent PTH-like polypeptide. The compositions and methods are useful in the treatment of osteoarthritis, cartilage defects and in related tissue repair.
    Type: Grant
    Filed: March 26, 1996
    Date of Patent: December 23, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Gary Hattersley, Vicki A. Rosen
  • Methods of inducting formation of tendon and/or ligament tissue comprising administering BMP-12, BMP-13, and/or MP-52
    Patent number: 5658882
    Abstract: The present invention relates to methods for the induction of tendon/ligament-like tissue formation, wound healing and ligament and other tissue repair, using a composition comprising BMP-12, BMP-13 or MP-52, or combinations of the above.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: August 19, 1997
    Assignees: Genetics Institute, Inc., President and Fellows of Harvard College
    Inventors: Anthony J. Celeste, John M. Wozney, Vicki A. Rosen, Neil M. Wolfman, Gerald H. Thomsen, Douglas A. Melton
  • Bone morphogenic protein-5(BMP-5) and DNA encoding same
    Patent number: 5635373
    Abstract: Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 3, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Vicki A. Rosen, Elizabeth A. Wang
  • Compositions comprising bone morphogenetic protein-2 (BMP-2)
    Patent number: 5631142
    Abstract: Purified BMP-2 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: May 20, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki A. Rosen
  • BMP-2 products
    Patent number: 5618924
    Abstract: Purified BMP-2 proteins and processes for producing them are disclosed. They may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: April 8, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki Rosen
  • Bone morphogenetic protein 5(BMP-5) compositions
    Patent number: 5543394
    Abstract: Purified BMP-5 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: August 6, 1996
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Vicki A. Rosen, Elizabeth A. Wang
  • BMP-6 proteins
    Patent number: 5459047
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: October 17, 1995
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • Methods for producing BMP-7 proteins
    Patent number: 5366875
    Abstract: Purified BMP-7 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: September 24, 1991
    Date of Patent: November 22, 1994
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen
  • DNA sequences encoding BMP-6 proteins
    Patent number: 5187076
    Abstract: Purified BMP-6 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: March 7, 1990
    Date of Patent: February 16, 1993
    Assignee: Genetics Institute, Inc.
    Inventors: John M. Wozney, Elizabeth A. Wang, Vicki A. Rosen, Anthony J. Celeste
  • DNA sequences encoding the osteoinductive proteins
    Patent number: 5166058
    Abstract: Purified BMP-2 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and cartilage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: July 11, 1989
    Date of Patent: November 24, 1992
    Assignee: Genetics Institute, Inc.
    Inventors: Elizabeth A. Wang, John M. Wozney, Vicki A. Rosen
  • DNA sequences encoding BMP-7 proteins
    Patent number: 5141905
    Abstract: Purified BMP-7 proteins and processes for producing them are disclosed. The proteins may be used in the treatment of bone and/or cartlage defects and in wound healing and related tissue repair.
    Type: Grant
    Filed: November 17, 1989
    Date of Patent: August 25, 1992
    Inventors: Vicki A. Rosen, Elizabeth A. Wang, John M. Wozney