Patents by Inventor Vicky Gavrias

Vicky Gavrias has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polynucleotide constructs
    Patent number: 7754944
    Abstract: Synthetic modular polynucleotide constructs are useful for gene expression in plants, methods for making and using such constructs, and plants transformed with such constructs. The constructs comprise unique restriction sites for each modular element and may further comprise polynucleotide identifier sequences.
    Type: Grant
    Filed: April 2, 2007
    Date of Patent: July 13, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Changlin Fu, Brian Hauge, Vicky Gavrias
  • Polynucleotide Constructs
    Publication number: 20070234442
    Abstract: Synthetic modular polynucleotide constructs are useful for gene expression in plants, methods for making and using such constructs, and plants transformed with such constructs. The constructs comprise unique restriction sites for each modular element and may further comprise polynucleotide identifier sequences.
    Type: Application
    Filed: April 2, 2007
    Publication date: October 4, 2007
    Inventors: Changlin Fu, Brian Hauge, Vicky Gavrias
  • Aspergillus fumigatus auxotrophs, auxotrophic markers and polynucleotides encoding same
    Patent number: 6337388
    Abstract: This invention relates to newly identified auxotrophs, polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production and isolation of such polynucleotides and polypeptides. More particularly, the polynucleotides and polypeptides of the present invention have been putatively identified as being very important to the growth and/or reproduction of Aspergillus fumigatus.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: January 8, 2002
    Assignee: Millenium Pharmaceuticals, Inc.
    Inventor: Vicky Gavrias
  • Identification of eukaryotic growth-related genes and promoter isolation vector and method of use
    Patent number: 6291218
    Abstract: A polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth, is provided. A maltose responsive promoter (MRP) isolated using the promoter library of the invention is also described. The present invention also provides a vector for isolation of a eukaryotic regulatory polynucleotide, i.e., promoter. The vector is useful in the method of the invention which comprises identifying a eukaryotic regulatory polynucleotide, i.e., promoter region, by complementing the growth of an auxotrophic host cell containing the vector of the invention, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome by targeted integration. Also provided is a library containing host cells having the vector of the invention integrated in the chromosome of the host cell.
    Type: Grant
    Filed: June 25, 1998
    Date of Patent: September 18, 2001
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Yigal Koltin, Perry Riggle, Vicky Gavrias, Chris Bulawa, Kenneth R. Winter
  • Identification of eukaryotic growth-related genes and promoter isolation vector and method of use
    Patent number: 6251593
    Abstract: A polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth, is provided. A maltose responsive promoter (MRP) isolated using the promoter library of the invention is also described. The present invention also provides a vector for isolation of a eukaryotic regulatory polynucleotide, i.e., promoter. The vector is useful in the method of the invention which comprises identifying a eukaryotic regulatory polynucleotide, i.e., promoter region, by complementing the growth of an auxotrophic host cell containing the vector of the invention, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome by targeted integration. Also provided is a library containing host cells having the vector of the invention integrated in the chromosome of the host cell.
    Type: Grant
    Filed: May 27, 1998
    Date of Patent: June 26, 2001
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Yigal Koltin, Perry Riggle, Vicky Gavrias, Chris Bulawa, Kenneth R. Winter
  • Aspergillus fumigatus auxotrophs, auxotrophic markers and polynucleotides encoding same
    Patent number: 6090581
    Abstract: This invention relates to newly identified auxotrophs, polynucleotides, polypeptides encoded by such polynucleotides, the use of such polynucleotides and polypeptides, as well as the production and isolation of such polynucleotides and polypeptides. More particularly, the polynucleotides and polypeptides of the present invention have been putatively identified as being very important to the growth and/or reproduction of Aspergillus fumigatus.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: July 18, 2000
    Assignee: Millenium Pharmaceuticals, Inc.
    Inventor: Vicky Gavrias
  • Identification of eukaryotic growth-related genes and promoter isolation vector and method of use
    Patent number: 6020133
    Abstract: A polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth, is provided. A maltose responsive promoter (MRP) isolated using the promoter library of the invention is also described.The present invention also provides a vector for isolation of a eukaryotic regulatory polynucleotide, i.e., promoter. The vector is useful in the method of the invention which comprises identifying a eukaryotic regulatory polynucleotide, i.e., promoter region, by complementing the growth of an auxotrophic host cell containing the vector of the invention, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome by targeted integration. Also provided is a library containing host cells having the vector of the invention integrated in the chromosome of the host cell.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: February 1, 2000
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Yigal Koltin, Perry Riggle, Vicky Gavrias, Chris Bulawa, Ken Winter
  • Identification of eukaryotic growth-related genes and promoter isolation vector and method of use
    Patent number: 5824545
    Abstract: A polynucleotide encoding chitin synthase (CHS1), an enzyme essential for cell wall synthesis and yeast cell growth, is provided. A maltose responsive promoter (MRP) isolated using the promoter library of the invention is also described.The present invention also provides a vector for isolation of a eukaryotic regulatory polynucleotide, i.e., promoter. The vector is useful in the method of the invention which comprises identifying a eukaryotic regulatory polynucleotide, i.e., promoter region, by complementing the growth of an auxotrophic host cell containing the vector of the invention, which includes a promoter region operably linked to a promoterless auxotrophic gene. The vector is introduced into the host cell chromosome by targeted integration. Also provided is a library containing host cells having the vector of the invention integrated in the chromosome of the host cell.
    Type: Grant
    Filed: November 1, 1995
    Date of Patent: October 20, 1998
    Assignee: Millennium Pharaceuticals, Inc.
    Inventors: Yigal Koltin, Perry Riggle, Vicky Gavrias, Chris Bulawa, Ken Winter