Patents by Inventor Victor Chengwei Shi

Victor Chengwei Shi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL USE
    Publication number: 20220133694
    Abstract: The present invention relates to novel methods and pharmaceutical compositions for the treatment of heart failure in a patient.
    Type: Application
    Filed: July 9, 2021
    Publication date: May 5, 2022
    Inventors: Adel Remond RIZKALA, Victor Chengwei SHI, Fabian CHEN
  • Sacubitril-valsartan dosage regimen for treating heart failure
    Patent number: 11058667
    Abstract: The present invention relates to sacubitril-valsartan dosage regimens for the treatment of heart failure in a patient.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: July 13, 2021
    Assignee: Novartis AG
    Inventors: Adel Remond Rizkala, Victor Chengwei Shi, Fabian Chen
  • NEW USE
    Publication number: 20210077461
    Abstract: The present invention relates to methods and pharmaceutical compositions for the prevention or in delaying time to first occurrence of mortality, in particular cardiovascular death, and/or of cardiovascular hospitalizations in a patient suffering from chronic systolic heart failure, comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of an Angiotensin Receptor Neprilysin inhibitor (ARNi) or of a combination of an Angiotensin Receptor Blocker (ARB) with a Neutral Endopeptidase inhibitor (NEPi) or with a NEPi pro-drug to said patient.
    Type: Application
    Filed: November 24, 2020
    Publication date: March 18, 2021
    Inventors: Victor Chengwei SHI, Martin LEFKOWITZ, Adel Remond RIZKALA
  • SACUBITRIL-VALSARTAN DOSAGE REGIMEN FOR TREATING HEART FAILURE
    Publication number: 20180125820
    Abstract: The present invention relates to sacubitril-valsartan dosage regimens for the treatment of heart failure in a patient.
    Type: Application
    Filed: May 9, 2016
    Publication date: May 10, 2018
    Inventors: Adel Remond Rizkala, Victor Chengwei SHI, Fabian CHEN
  • NEW USE
    Publication number: 20160213646
    Abstract: The present invention relates to methods and pharmaceutical compositions for the prevention or in delaying time to first occurrence of mortality, in particular cardiovascular death, and/or of cardiovascular hospitalizations in a patient suffering from chronic systolic heart failure, comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of an Angiotensin Receptor Neprilysin inhibitor (ARNi) or of a combination of an Angiotensin Receptor Blocker (ARB) with a Neutral Endopeptidase inhibitor (NEPi) or with a NEPi pro-drug to said patient.
    Type: Application
    Filed: August 26, 2014
    Publication date: July 28, 2016
    Applicant: NOVARTIS AG
    Inventors: Victor Chengwei SHI, Martin LEFKOWITZ, Adel Remond RIZKALA
  • New Use
    Publication number: 20160206597
    Abstract: The present invention relates to methods and pharmaceutical compositions for renal protection in a mammal in need thereof, such as a mammal having a disease manifested by atrial enlargement and/or remodeling or suffering from hypertension or heart failure or being prone to suffering from hypertension and/or heart failure, comprising administration of a therapeutically effective amount, or a prophylactically effective amount, of an Angiotensin Receptor Neprilysin inhibitor (ARNi) or of a combination of an Angiotensin Receptor Blocker (ARB) with a Neutral Endopeptidase inhibitor (NEPi) or with a NEPi pro-drug to said mammal.
    Type: Application
    Filed: August 26, 2013
    Publication date: July 21, 2016
    Inventors: Toni Lynne Bransford, Bryan BURKEY, Thomas LANGENICKEL, Martin LEFKOWITZ, Victor Chengwei SHI
  • Tolerance-inducing thy-marrow composite tissue construct and organ
    Publication number: 20040025198
    Abstract: Thy-marrow composite tissue construct and composite organ for creating hematopoietic chimerism and inducing long-term stable immunological tolerance in a transplant recipient, especially a human xenotransplant recipient of a non-human mammalian (e.g., pig) organ.
    Type: Application
    Filed: June 11, 2003
    Publication date: February 5, 2004
    Inventors: Philip Lake, Victor Chengwei Shi
  • Tolerance-inducing thy-marrow composite tissue construct and organ
    Publication number: 20020152490
    Abstract: Thy-marrow composite tissue construct and composite organ for creating hematopoietic chimerism and inducing long-term stable immunological tolerance in a transplant recipient, especially a human xenotransplant recipient of a non-human mammalian (e.g., pig) organ.
    Type: Application
    Filed: April 12, 2001
    Publication date: October 17, 2002
    Inventors: Philip Lake, Victor Chengwei Shi
  • Treatment of arteriosclerosis
    Patent number: 6365619
    Abstract: A method is disclosed of treating transplant-associated arteriosclerosis in a mammal which comprises administering to a mammal, preferably man, in need of such treatment an effective amount of a VLA-4 antagonist of formula I and a VCAM-1 inhibitor of formula II.
    Type: Grant
    Filed: July 22, 1999
    Date of Patent: April 2, 2002
    Assignee: Novartis AG
    Inventor: Victor Chengwei Shi