Patents by Inventor Victor Guzov

Victor Guzov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EVOLUTION OF BT TOXINS
    Publication number: 20230220016
    Abstract: The disclosure provides amino acid sequence variants of Bacillus thuringiensis (Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins.
    Type: Application
    Filed: October 26, 2022
    Publication date: July 13, 2023
    Applicants: President and Fellows of Harvard College, Monsanto Company
    Inventors: David R. Liu, Ahmed Hussein Badran, Victor Guzov, Tom Malvar, Prashanth Vishwanath, Jeff Nageotte, Qing Huai, Melissa Kemp
  • Evolution of toxins
    Patent number: 11524983
    Abstract: The disclosure provides amino acid sequence variants of Bacillus thuringiensis (Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: December 13, 2022
    Assignees: President and Fellows of Harvard College, Monsanto Company
    Inventors: David R. Liu, Ahmed Hussein Badran, Victor Guzov, Tom Malvar, Prashanth Vishwanath, Jeff Nageotte, Qing Huai, Melissa Kemp
  • EVOLUTION OF BT TOXINS
    Publication number: 20180057545
    Abstract: The disclosure provides amino acid sequence variants of Bacillus thuringiensis (Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins.
    Type: Application
    Filed: July 22, 2016
    Publication date: March 1, 2018
    Inventors: David R. Liu, Ahmed Hussein Badran, Victor Guzov, Tom Malvar, Prashanth Vishwanath, Jeff Nageotte, Qing Huai, Melissa Kemp
  • EVOLUTION OF BT TOXINS
    Publication number: 20170029473
    Abstract: The disclosure provides amino acid sequence variants of Bacillus thuringiensis (Bt) toxins and methods of producing the same. Some aspects of this disclosure provide methods for generating Bt toxin variants by continuous directed evolution. Some aspects of this disclosure provide compositions and methods for pest control using the disclosed variant Bt toxins.
    Type: Application
    Filed: July 22, 2016
    Publication date: February 2, 2017
    Inventors: David R. Liu, Ahmed Hussein Badran, Victor Guzov, Tom Malvar, Prashanth Vishwanath, Jeff Nageotte, Qing Huai, Melissa Kemp
  • Insect inhibitory Bacillus thuringiensis proteins, fusions, and methods of use therefor
    Publication number: 20070208168
    Abstract: Novel insect inhibitory proteins are disclosed comprising two different components, both of which are required for biological activity. Various methods of linking both components together, so that a single protein provides insect inhibitory activity, are disclosed. Also disclosed are novel Bacillus thuringiensis nucleic acid sequences encoding Coleopteran-inhibitory crystal proteins, designated tIC100 (29-kDa) and tlC101 (14-kDa). Also disclosed are methods of making and using nucleic acid sequences in the development of the transgenic plant cells containing the novel nucleic acid sequences disclosed herein.
    Type: Application
    Filed: April 27, 2007
    Publication date: September 6, 2007
    Inventors: Victor Guzov, Thomas Malvar, James Roberts, Sakuntala Sivasupramaniam