Abstract: The present invention provides a liposomal topical formulation or a liposomal topical formulation base having barrier-forming siliconic components, methods for making the same, and methods for using the same in the treatment of dermatological diseases and conditions, including male pattern baldness.

Abstract: The present disclosure provides a liposomal topical formulation comprising dutasteride having barrier-forming siliconic components, methods for making the same, and methods for using the same in the treatment of dermatological diseases and conditions, including male pattern baldness.

Abstract: The present invention provides a liposomal topical formulation or a liposomal topical formulation base having barrier-forming siliconic components, methods for making the same, and methods for using the same in the treatment of dermatological diseases and conditions, including male pattern baldness.

Abstract: Various embodiments provide methods for forming a diamond heat spreader and integrating the diamond heat spreader with a heat source without generating voids at the interface. In one embodiment, a semiconductor layer can be epitaxially formed on a diamond substrate having a desirably low surface root mean square (RMS) roughness. The semiconductor epi-layer can be used as an interface layer for bonding the diamond substrate to the heat source to provide efficient heat spreading.

Abstract: A method and apparatus for cooling a high power laser oscillator or amplifier is disclosed in which a plurality of laser gain media that are configured such that the width of the media is greater than the thickness of the media, are sandwiched between pairs of optically transparent materials having high thermal conductivity. In this way, a shortened thermal path is created from the face surface of the laser gain media axially via the optically transparent heat conductor to an external heat exchange system. This provides an increased level of cooling of the interior of the laser gain media and avoids the deleterious effects caused by over heating of the laser gain media particularly with large effective cross sections desired for high power and/or high pulse repetition and high pulse energy operation.

Abstract: An active optical amplifier in which a unitary optical amplifier constructed from a unitary optically transparent chip that has been doped so as to be optically active, amplifies incoming signal photons when excited by a pump laser of sufficient energy. The unitary optical amplifier receives input photons and pump laser energy and provides output photons that have the same spatial orientation and phase as the corresponding input photons. A laser direction and ranging (LADAR) may be constructed from the active optical amplifier by further including first imaging optics to focus the input photons onto the surface of the unitary optical amplifier and second imaging optics to focus the output photons from the active unitary optical amplifier onto a focal plane image sensor array. The electronic signals from the focal plane image sensor array may then be displayed on a conventional display.

Abstract: An optical correlator is used to detect the presence of a target in a laser detection and ranging (LADAR) system by analyzing the return signal, and to provide initial estimates of the targets range and velocity to the LADAR receiver. The optical correlator includes an acoustic optical Bragg cell that deflects an input laser signal using the received and down-converted LADAR signal. An integrating optical detector is disposed to receive the optical outputs of the acoustic optical Bragg cell and an optical processor analyzes and processes the integrating optical detector data. The integrating optical detector integrates the optical outputs of the Bragg cell over time and the integrating optical detector output is sampled over a sampling period so that target detection is uncorrelated to noise.

Abstract: An optical correlator is used to detect the presence of a target in a laser detection and ranging (LADAR) system by analyzing the return signal, and to provide initial estimates of the targets range and velocity to the LADAR receiver. The optical correlator includes an acoustic optical Bragg cell that deflects an input laser signal using the received and down-converted LADAR signal. A the integrating optical detector is disposed to receive the optical outputs of the acoustic optical Bragg cell and an optical processor analyzes and processes the integrating optical detector data. The integrating optical detector integrates the optical outputs of the Bragg cell over time and the integrating optical detector output is sampled over a sampling period so that target detection is uncorrelated to noise.

Abstract: A method and apparatus for cooling a high power laser oscillator or amplifier is disclosed in which a plurality of laser gain media that are configured such that the width of the media is greater than the thickness of the media, are sandwiched between pairs of optically transparent materials having high thermal conductivity. In this way, a shortened thermal path is created from the face surface of the laser gain media axially via the optically transparent heat conductor to an external heat exchange system. This provides an increased level of cooling of the interior of the laser gain media and avoids the deleterious effects caused by over heating of the laser gain media particularly with large effective cross sections desired for high power and/or high pulse repetition and high pulse energy operation.

Abstract: An active optical amplifier in which a unitary optical amplifier constructed from a unitary optically transparent chip that has been doped so as to be optically active, amplifies incoming signal photons when excited by a pump laser of sufficient energy. The unitary optical amplifier receives input photons and pump laser energy and provides output photons that have the same spatial orientation and phase as the corresponding input photons. A laser direction and ranging (LADAR) may be constructed from the active optical amplifier by further including first imaging optics to focus the input photons onto the surface of the unitary optical amplifier and second imaging optics to focus the output photons from the active unitary optical amplifier onto a focal plane image sensor array. The electronic signals from the focal plane image sensor array may then be displayed on a conventional display.