Patents by Inventor Victor Johann Raul Jeger

Victor Johann Raul Jeger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250035629
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being MR-proADM, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: sFlt-1, GDF15 and ESM1, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.
    Type: Application
    Filed: September 28, 2022
    Publication date: January 30, 2025
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240248098
    Abstract: The present invention concerns the field of diagnostics. Specifically. it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject. said first biomarker being NGAL. determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: HBP (Heparin-binding protein). Aspartate aminotransferase. Bilirubin. Alanine aminotransferase. ESM-1 and a BNP-type peptide. comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers. and assessing said subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker being NGAL and a second biomarker selected from the group consisting of: HBP (Heparin-binding protein). Aspartate aminotransferase. Bilirubin.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 25, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240230676
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being ESM-1, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is Creatinine or a Cystatin C, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker being ESM-1 and a second biomarker being Creatinine or a Cystatin C or a detection agent specifically binding to said first biomarker and a detection agent specifically binding to said second biomarker for assessing a subject with suspected infection.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 11, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240230674
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being STREM1, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: Aspartate aminotransferase, Bilirubin, ESM-1, HBP (Heparin-binding protein), a cardiac Troponin, Alanine aminotransferase, and IL6, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 11, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240230673
    Abstract: The present invention relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being GDF-15, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: sFLT1, Cystatin C, IGFBP-7, Bilirubin, ESM-1, sTREM-1, Procalcitonin, cardiac Troponin, BNP-type peptide, Alanine aminotransferase, and Aspartate aminotransferase, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 11, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240230675
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being sFlt1, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: Cystatin C, IGFBP7, a cardiac Troponin, Creatinine, STREM1, PCT and Bilirubin, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 11, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240230672
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being Presepsin, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: GDF-15, Creatinine, sFlt1, IGFBP7, sTREM1, Cystatin C and PSP (Pancreatic Stone Protein), comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 11, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240221958
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being PCT, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: a cardiac Troponin, Creatinine, a BNP-type peptide, sTREM1, ESM-1, Haptoglobin, Heparin binding protein (HBP) and Aspartate aminotransferase, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 4, 2024
    Inventors: Felix Gruenewald, Martin Klammer, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen, Victor Johann Raul Jeger, Philipp Schuetz, Maria von Holtey
  • Publication number: 20240219405
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being IL-6, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is Creatinine or a cardiac Troponin, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker being IL-6 and a second biomarker being a cardiac Troponin or Creatinine or a detection agent specifically binding to said first biomarker and a detection agent specifically binding to said second biomarker for assessing a subject with suspected infection.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 4, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
  • Publication number: 20240219404
    Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being IGFBP7, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: PCT, IL6, a cardiac Troponin, Albumin, CRP, Bilirubin, Ferritin, ESM-1, Aspartate aminotransferase, a BNP-type peptide, Alanine aminotransferase, Creatinine, and suPAR, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 4, 2024
    Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen