Patents by Inventor Victor Johann Raul Jeger
Victor Johann Raul Jeger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250035629Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being MR-proADM, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: sFlt-1, GDF15 and ESM1, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.Type: ApplicationFiled: September 28, 2022Publication date: January 30, 2025Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240248098Abstract: The present invention concerns the field of diagnostics. Specifically. it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject. said first biomarker being NGAL. determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: HBP (Heparin-binding protein). Aspartate aminotransferase. Bilirubin. Alanine aminotransferase. ESM-1 and a BNP-type peptide. comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers. and assessing said subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker being NGAL and a second biomarker selected from the group consisting of: HBP (Heparin-binding protein). Aspartate aminotransferase. Bilirubin.Type: ApplicationFiled: April 29, 2022Publication date: July 25, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240230676Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being ESM-1, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is Creatinine or a Cystatin C, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker being ESM-1 and a second biomarker being Creatinine or a Cystatin C or a detection agent specifically binding to said first biomarker and a detection agent specifically binding to said second biomarker for assessing a subject with suspected infection.Type: ApplicationFiled: April 29, 2022Publication date: July 11, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240230674Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being STREM1, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: Aspartate aminotransferase, Bilirubin, ESM-1, HBP (Heparin-binding protein), a cardiac Troponin, Alanine aminotransferase, and IL6, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.Type: ApplicationFiled: April 29, 2022Publication date: July 11, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240230673Abstract: The present invention relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being GDF-15, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: sFLT1, Cystatin C, IGFBP-7, Bilirubin, ESM-1, sTREM-1, Procalcitonin, cardiac Troponin, BNP-type peptide, Alanine aminotransferase, and Aspartate aminotransferase, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.Type: ApplicationFiled: April 29, 2022Publication date: July 11, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240230675Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being sFlt1, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: Cystatin C, IGFBP7, a cardiac Troponin, Creatinine, STREM1, PCT and Bilirubin, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.Type: ApplicationFiled: April 29, 2022Publication date: July 11, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240230672Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being Presepsin, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: GDF-15, Creatinine, sFlt1, IGFBP7, sTREM1, Cystatin C and PSP (Pancreatic Stone Protein), comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.Type: ApplicationFiled: April 29, 2022Publication date: July 11, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240221958Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being PCT, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: a cardiac Troponin, Creatinine, a BNP-type peptide, sTREM1, ESM-1, Haptoglobin, Heparin binding protein (HBP) and Aspartate aminotransferase, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.Type: ApplicationFiled: April 29, 2022Publication date: July 4, 2024Inventors: Felix Gruenewald, Martin Klammer, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen, Victor Johann Raul Jeger, Philipp Schuetz, Maria von Holtey
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Publication number: 20240219405Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being IL-6, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is Creatinine or a cardiac Troponin, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation. The invention also relates to the use of a first biomarker being IL-6 and a second biomarker being a cardiac Troponin or Creatinine or a detection agent specifically binding to said first biomarker and a detection agent specifically binding to said second biomarker for assessing a subject with suspected infection.Type: ApplicationFiled: April 29, 2022Publication date: July 4, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen
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Publication number: 20240219404Abstract: The present invention concerns the field of diagnostics. Specifically, it relates to a method for assessing a subject with suspected infection comprising the steps of determining the amount of a first biomarker in a sample of the subject, said first biomarker being IGFBP7, determining the amount of a second biomarker in a sample of the subject, wherein said second biomarker is selected from the group consisting of: PCT, IL6, a cardiac Troponin, Albumin, CRP, Bilirubin, Ferritin, ESM-1, Aspartate aminotransferase, a BNP-type peptide, Alanine aminotransferase, Creatinine, and suPAR, comparing the amounts of the biomarkers to references for said biomarkers and/or calculating a score for assessing the subject with suspected infection based on the amounts of the biomarkers, and assessing said subject based on the comparison and/or the calculation.Type: ApplicationFiled: April 29, 2022Publication date: July 4, 2024Inventors: Felix Gruenewald, Victor Johann Raul Jeger, Martin Klammer, Philipp Schuetz, Maria von Holtey, Stephen Weber, Heike Wegmeyer, Ursula-Henrike Wienhues-Thelen