Patents by Inventor Victor Krasnykh

Victor Krasnykh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adenoviruses expressing heterologous tumor-associated antigens
    Patent number: 11155599
    Abstract: The present invention is directed to adenoviruses for use in cancer therapy which comprise one or more heterologous nucleic acid sequences encoding a tumor antigen, whereby the adenovirus expresses the tumor antigen(s) on its surface.
    Type: Grant
    Filed: February 1, 2013
    Date of Patent: October 26, 2021
    Assignee: Board of Regents, The University of Texas System
    Inventors: Juan Fueyo-Margareto, Candelaria Gomez-Manzano, W. K. Alfred Yung, Victor Krasnykh, Hong Jiang
  • ADENOVIRUSES EXPRESSING HETEROLOGOUS TUMOR-ASSOCIATED ANTIGENS
    Publication number: 20140377294
    Abstract: The present invention is directed to adenoviruses for use in cancer therapy which comprise one or more heterologous nucleic acid sequences encoding a tumor antigen, whereby the adenovirus expresses the tumor antigen(s) on its surface.
    Type: Application
    Filed: February 1, 2013
    Publication date: December 25, 2014
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Juan Fueyo-Margareto, Candelaria Gomez-Manzano, W.K. Alfred Yung, Victor Krasnykh, Hong Jiang
  • Infectivity-enhanced conditionally-replicative adenovirus and uses thereof
    Patent number: 6824771
    Abstract: A modified adenovirus capable of overcoming the problem of low level of coxsackle-adenovirus receptor (CAR) expression on tumor cells and methods of using such adenovirus are provided. The fiber protein of the adenovirus is modified by insertion or replacement so as to target the adenovirus to tumor cells, and the replication of the modified adenovirus is limited to tumor cells due to mutations in E1a or E1b genes.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: November 30, 2004
    Assignee: The UAB Research Foundation
    Inventors: David T. Curiel, Victor Krasnykh, Ramon Alemany, Igor Dmitriev
  • Infectivity-enhanced conditionally-replicative adenovirus and uses thereof
    Publication number: 20040175362
    Abstract: A modified adenovirus capable of overcoming the problem of low level of coxsackie-adenovirus receptor (CAR) expression on tumor cells and methods of using such adenovirus are provided. The fiber protein of the adenovirus is modified by insertion or replacement so as to target the adenovirus to tumor cells, and the replication of the modified adenovirus is limited to tumor cells due to specific promoter control or mutations in E1a or E1b genes.
    Type: Application
    Filed: October 30, 2003
    Publication date: September 9, 2004
    Inventors: David T. Curiel, Victor Krasnykh, Ramon Alemany, Igor Dmitriev