Patents by Inventor Victor L. Schuster

Victor L. Schuster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULE PROSTAGLADIN TRANSPORT INHIBITORS
    Publication number: 20220402881
    Abstract: The disclosure provides compounds of Formula 1, and the pharmaceutically acceptable salts thereof. The variables in Formula 1, e.g. X1-X5, A1, A2, and R1-R4 are described herein. Such compounds are useful as prostaglandin transport (PGT) inhibitors. The disclosure further includes pharmaceutical compositions comprising a compound of Formula 1 or salt thereof and methods of using compounds of Formula 1 and salts thereof to treat diseases and disorders mediated, at least in part, by prostaglandin levels or cyclooxygenase activity. Such diseases and disorders include painful and inflammatory conditions.
    Type: Application
    Filed: November 2, 2020
    Publication date: December 22, 2022
    Inventors: Victor L. SCHUSTER, William GREENLEE, Evripidis GAVATHIOTIS
  • Treatment of obesity and pulmonary arterial hypertension
    Patent number: 9603852
    Abstract: Disclosed are methods and compositions for treating pulmonary arterial hypertension and/or obesity using inhibitors of prostaglandin transporter (PGT) activity.
    Type: Grant
    Filed: June 17, 2014
    Date of Patent: March 28, 2017
    Assignee: Albert Einstein College of Medicine, Inc.
    Inventors: Victor L. Schuster, Yuling Chi
  • TREATMENT OF OBESITY AND PULMONARY ARTERIAL HYPERTENSION
    Publication number: 20160113933
    Abstract: Disclosed are methods and compositions for treating pulmonary arterial hypertension and/or obesity using inhibitors of prostaglandin transporter (PGT) activity.
    Type: Application
    Filed: June 17, 2014
    Publication date: April 28, 2016
    Applicant: Albert Einstein College of Medicine, Inc.
    Inventors: Victor L. Schuster, Yuling Chi
  • Prostaglandin transporter inhibitors
    Patent number: 9144573
    Abstract: The present invention generally relates to prostaglandin transport. More specifically, the invention is directed to compounds that inhibit prostaglandin transport and subsequent COX-2 induction, and methods relating thereto.
    Type: Grant
    Filed: July 23, 2012
    Date of Patent: September 29, 2015
    Assignees: Albert Einstein College of Medicine of Yeshiva University, New York University
    Inventors: Victor L. Schuster, Yuling Chi, Young-Tae Chang, Jaeki Min
  • Prostaglandin transporter inhibitors and uses thereof
    Patent number: 8952150
    Abstract: Disclosed are compounds for inhibiting prostaglandin transporter (PGT) activity, pharmaceuticals compositions including the compounds, and methods of treating subjects using the compounds.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: February 10, 2015
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Victor L. Schuster, Yuling Chi, Andrew S. Wasmuth, Richard S. Pottorf, Gary L. Olson
  • PROSTAGLANDIN TRANSPORTER INHIBITORS
    Publication number: 20130171171
    Abstract: The present invention generally relates to prostaglandin transport. More specifically, the invention is directed to compounds that inhibit prostaglandin transport and subsequent COX-2 induction, and methods relating thereto.
    Type: Application
    Filed: July 23, 2012
    Publication date: July 4, 2013
    Inventors: Victor L. Schuster, Yuling Chi, Young-Tae Chang, Jaeki Min
  • PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF
    Publication number: 20120238577
    Abstract: Disclosed are compounds for inhibiting prostaglandin transporter (PGT) activity, pharmaceuticals compositions including the compounds, and methods of treating subjects using the compounds.
    Type: Application
    Filed: September 20, 2010
    Publication date: September 20, 2012
    Applicant: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Victor L. Schuster, Yuling Chi, Andrew S. Wasmuth, Richard S. Pottorf, Gary L. Olson
  • Prostaglandin transporter inhibitors
    Patent number: 8227466
    Abstract: Provided are methods of inhibiting prostaglandin transporter (PGT) activity in mammals. Also provided are methods of determining whether a test compound is an inhibitor of a prostaglandin transporter. Additionally provided are compounds that inhibit prostaglandin transporter activity, and pharmaceutical compositions of those compounds. Methods of inhibiting COX-2 in a mammal are also provided. Additionally, methods of treating pain or inflammation in a mammal are provided.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: July 24, 2012
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Victor L. Schuster, Yuling Chi, Young-Tae Chang, Jaeki Min
  • Prostaglandin Transporter Inhibitors
    Publication number: 20090233933
    Abstract: Provided are methods of inhibiting prostaglandin transporter (PGT) activity in mammals. Also provided are methods of determining whether a test compound is an inhibitor of a prostaglandin transporter. Additionally provided are compounds that inhibit prostaglandin transporter activity, and pharmaceutical compositions of those compounds. Methods of inhibiting COX-2 in a mammal are also provided. Additionally, methods of treating pain or inflammation in a mammal are provided.
    Type: Application
    Filed: May 15, 2007
    Publication date: September 17, 2009
    Applicants: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNI, NEW YORK UNIVERSITY
    Inventors: Victor L. Schuster, Yuling Chi, Young-Tae Chang, Jaeki Min
  • Human prostaglandin transporter
    Patent number: 5792851
    Abstract: The present invention provides a purified and isolated nucleic acid encoding human prostaglandin transporter (hPGT). The present invention also provides a vector comprising a nucleic acid encoding human prostaglandin transporter (hPGT), a cell stably transformed with this vector, as well as a method for producing a recombinant, human prostaglandin transporter (hPGT). The present invention also provides a purified and isolated human prostaglandin transporter (hPGT), and an antibody immunoreactive with this protein. The present invention further provides a method for evaluating the uptake of a selected prostaglandin by cells expressing nucleic acid encoding human prostaglandin transporter (hPGT).
    Type: Grant
    Filed: September 3, 1996
    Date of Patent: August 11, 1998
    Assignee: Albert Einstin College of Medicine of Yeshiva University, a Division of Yeshiva University
    Inventors: Victor L. Schuster, Run Lu