Abstract: The present disclosure relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer's Disease or a tauopathy disease.

Abstract: Systems and methods for determining an optimized medical plan using a machine learning-based model. The method includes receiving benchmarking data from a database including commercial claims data and past expense data. The method further includes receiving participant data from a user interface on a user device. The participant data includes demographic data, geographic data, and a past health service profile. The method also includes determining eligibility data and calculating base expense data based on the benchmarking data and the participant data. The method further includes calibrating the base expense data using the past expense data and a linear model. The method also includes calculating predicted expense data based on the calibrated base expense data. The method further includes determining medical plan configurations based on the predicted expense data and the eligibility data. The method also includes generating for display the medical plan configurations on the user device.

Abstract: A method and apparatus for treating slurries of organic solids is disclosed. A slurry of organic solids is admixed with hydrogen peroxide, followed by exposure to microwave irradiation resulting in the heating of the mixture and enhanced hydrolysis of the organic solids. The treated slurry of organic solids can then be further treated in a variety of downstream processes, including solid separation, digestion and fermentation. The supernatant portion of the treated slurry of organic solids can be a source from which to recover compounds such as nutrients (for example nitrogen, phosphate, potassium, magnesium, calcium) or industrial organic compounds (such as acetic acid, propionic acid, butyric acid), or as a source of readily biodegradable organic compounds for supplementing a biological wastewater treatment process, digester or fermenter.

Abstract: A method and apparatus for treating slurries of organic solids is disclosed. A slurry of organic solids is admixed with hydrogen peroxide, followed by exposure to microwave irradiation resulting in the heating of the mixture and enhanced hydrolysis of the organic solids. The treated slurry of organic solids can then be further treated in a variety of downstream processes, including solid separation, digestion and fermentation. The supernatant portion of the treated slurry of organic solids can be a source from which to recover compounds such as nutrients (for example nitrogen, phosphate, potassium, magnesium, calcium) or industrial organic compounds (such as acetic acid, propionic acid, butyric acid), or as a source of readily biodegradable organic compounds for supplementing a biological wastewater treatment process, digester or fermenter.

Abstract: A method and apparatus for treating slurries of organic solids is disclosed. A slurry of organic solids is admixed with hydrogen peroxide, followed by exposure to microwave irradiation resulting in the heating of the mixture and enhanced hydrolysis of the organic solids. The treated slurry of organic solids can then be further treated in a variety of downstream processes, including solid separation, digestion and fermentation. The supernatant portion of the treated slurry of organic solids can be a source from which to recover compounds such as nutrients (for example nitrogen, phosphate, potassium, magnesium, calcium) or industrial organic compounds (such as acetic acid, propionic acid, butyric acid), or as a source of readily biodegradable organic compounds for supplementing a biological wastewater treatment process, digester or fermenter.