Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: An illumination circuitry for a time-of-flight module for switching at least two illuminators, wherein the illumination circuitry is configured to: receive an input illumination signal from a time-of-flight sensor; and generate, based on the input illumination signal, synchronized first illumination signals for a first illuminator and second illumination signals for a second illuminator.

Abstract: A centerbody assembly includes a center tube, a forward bulkhead, an aft bulkhead, at least one baffle, and an outer skin. The center tube extends circumferentially about an axial centerline. The center tube extends between and to a first axial tube end and a second axial tube end. The forward bulkhead is mounted to the center tube at the first axial tube end. The aft bulkhead is mounted to the center tube at the second axial tube end. The at least one baffle extends axially from the forward bulkhead to the aft bulkhead. At least the forward bulkhead, the aft bulkhead, or the at least one baffle include one or more thermal beads. The outer skin circumscribes the center tube, the forward bulkhead, the aft bulkhead, and the at least one baffle to form an acoustic cavity radially inside the outer skin.

Abstract: Systems are disclosed relating to a weld module for weld training systems. In some examples, a weld module is configured for attachment to (and/or detachment from) a plug of a welding tool (e.g., welding torch, gun, stinger, foot pedal, etc.). The weld module may be configured to detect tool events based one or more signals received from the plug of the welding tool. The weld module may communicate the tool events to the weld training system for use during a weld simulation, for example.

Abstract: According to certain aspects of the present disclosure, a device is provided. The device includes a thin film of cobalt. A platinum layer is disposed on the thin film of cobalt. An aluminum layer is disposed on the platinum layer. The aluminum layer disposed on the platinum layer encapsulates the thin film of cobalt. A plurality of electrical contacts is in electrical communication with the thin film of cobalt. Two electrical contacts of the plurality of electrical contacts are configured to receive a write-current therebetween. Four electrical contacts of the plurality of contacts are configured for reading a 4-point resistance.

Abstract: Systems are disclosed relating to a weld module for weld training systems. In some examples, a weld module is configured for attachment to (and/or detachment from) a plug of a welding tool (e.g., welding torch, gun, stinger, foot pedal, etc.). The weld module may be configured to detect tool events based one or more signals received from the plug of the welding tool. The weld module may communicate the tool events to the weld training system for use during a weld simulation, for example.

Abstract: The disclosure is generally directed to in-vehicle entertainment systems and methods. An example method executed by processor of a vehicle may include displaying an iconic representation containing a first icon representing a musical instrument and a second icon representing a vehicle component. The processor may detect an assigning of the musical instrument to the vehicle component. The assigning may be carried out, for example, by a driver of the vehicle executing a drag-and-operation to overlap the first icon with second icon. The processor may then detect a physical contact made upon the vehicle component and generate, based on detecting the physical contact, a musical sound corresponding to the musical instrument.

Abstract: Systems for simulating joining operations, such as welding, are disclosed. In some examples, a system may use a mobile device for conducting welding simulations, such as for purposes of training. In some examples, the system may additionally, or alternatively, use modular workpieces. In some examples, the system may additionally, or alternatively, conduct the welding simulation based on one or more selected pieces of welding equipment.

Abstract: Systems for simulating joining operations, such as welding, are disclosed. In some examples, a system may use a desktop device for conducting welding simulations, such as for purposes of training. In some examples, the system may additionally, or alternatively, use modular workpieces. In some examples, the system may additionally, or alternatively, conduct the welding simulation based on one or more selected pieces of welding equipment.

Abstract: Systems are disclosed relating to a mobile device mounted to a welding helmet such that a wearer of the welding helmet can see a display of the mobile device when wearing the welding helmet. In some examples, the mobile device is mounted such that a camera of the mobile device is unobscured and positioned at approximately eye level, facing the same way the wearer's eyes are facing. In some examples, the simulated training environment may be presented to the user via the display screen of the mobile device, using images captured by the camera of the mobile device, when the mobile device is so mounted to the welding helmet.

Abstract: Systems are disclosed relating to a mobile device mounted to a welding helmet such that a wearer of the welding helmet can see a display of the mobile device when wearing the welding helmet. In some examples, the mobile device is mounted such that a camera of the mobile device is unobscured and positioned at approximately eye level, facing the same way the wearer's eyes are facing. In some examples, the simulated training environment may be presented to the user via the display screen of the mobile device, using images captured by the camera of the mobile device, when the mobile device is so mounted to the welding helmet.

Abstract: Systems for simulating joining operations, such as welding, are disclosed. In some examples, a system may use a mobile device for conducting welding simulations, such as for purposes of training. In some examples, the system may additionally, or alternatively, use modular workpieces. In some examples, the system may additionally, or alternatively, conduct the welding simulation based on one or more selected pieces of welding equipment.

Abstract: Systems for simulating joining operations, such as welding, are disclosed. In some examples, a system may use a mobile device for conducting welding simulations, such as for purposes of training. In some examples, the system may additionally, or alternatively, use modular workpieces. In some examples, the system may additionally, or alternatively, conduct the welding simulation based on one or more selected pieces of welding equipment.

Abstract: A system and method for validating proof of transit of network traffic through network nodes (N), the node (N) comprising a set of input interfaces (20) receiving incoming packets, a first module (A) to identify a matching route within a routing table (23) and storing means (22) to provide next modules (B, C, D) with two private keys if the packet is matched and/or the packet metadata includes OPoT information. The second module (B) decrypts the OPoT metadata using the first private key associated to the link of the node from which the incoming packets are received. The node (N) has SSS metadata to be processed by a third module (C) for the correct generation of cumulative validation parameters. When the SSS process is finished by the third module (C), the fourth module (D) re-encrypts the OPoT metadata using the second private key before packet forwarding to the subsequent node in the path through output interfaces (21).

Abstract: Systems for simulating joining operations, such as welding, are disclosed. In some examples, a system may use a mobile device for conducting welding simulations, such as for purposes of training. In some examples, the system may additionally, or alternatively, use modular workpieces. In some examples, the system may additionally, or alternatively, conduct the welding simulation based on one or more selected pieces of welding equipment.

Abstract: Systems are disclosed relating to a mobile device mounted to a welding helmet such that a wearer of the welding helmet can see a display of the mobile device when wearing the welding helmet. In some examples, the mobile device is mounted such that a camera of the mobile device is unobscured and positioned at approximately eye level, facing the same way the wearer's eyes are facing. In some examples, the simulated training environment may be presented to the user via the display screen of the mobile device, using images captured by the camera of the mobile device, when the mobile device is so mounted to the welding helmet.

Abstract: Systems are disclosed relating to a weld module for weld training systems. In some examples, a weld module is configured for attachment to (and/or detachment from) a plug of a welding tool (e.g., welding torch, gun, stinger, foot pedal, etc.). The weld module may be configured to detect tool events based one or more signals received from the plug of the welding tool. The weld module may communicate the tool events to the weld training system for use during a weld simulation, for example.

Abstract: A system and method for validating proof of transit of network traffic through network nodes (N), the node (N) comprising a set of input interfaces (20) receiving incoming packets, a first module (A) to identify a matching route within a routing table (23) and storing means (22) to provide next modules (B, C, D) with two private keys if the packet is matched and/or the packet metadata includes OPoT information. The second module (B) decrypts the OPoT metadata using the first private key associated to the link of the node from which the incoming packets are received. The node (N) has SSS metadata to be processed by a third module (C) for the correct generation of cumulative validation parameters. When the SSS process is finished by the third module (C), the fourth module (D) re-encrypts the OPoT metadata using the second private key before packet forwarding to the subsequent node in the path through output interfaces (21).

Abstract: The method comprising: receiving, a controller (106), traffic packets from a device, each one of said traffic packets including a VLAN tag indicating a destination of a second device; analyzing, by a first monitoring unit (101) during a period of time, the bytes content of said received packets and reporting said analysis to said controller (106); receiving, said controller (106), said plurality of different subcarriers to be used for said sending; adding, by a tag unit (102), an embedded S-VLAN tag to said analyzed packets identifying to which subcarrier and to which sliceable bandwidth variable transponder (105) each tagged traffic packets per destination is going to be sent; sending said S-VLAN tagged traffic packets to a switch (104), the latter forwarding them to a given port of said identified sliceable bandwidth variable transponder (105) for sending them via different sub-carriers to its corresponding destination, said plurality of different sub-carriers following a same or different path.

Abstract: The method updating the status of a network by means of a protocol of the control plane of said network and in response to a path request from at least a path computation client (PCC) pre-reserving during a reserved period of time (Tres), by at least one path computation element (PCE), a plurality of network resources in at least one traffic engineering database (TED) of the at least one PCE. The method dynamically modifying by a timer policy said reserved period of time (Tres) by at least using information data regarding the delay of said control plane. The system of the invention is adapted to implement the method of the invention.