Patents by Inventor Victor M. Sanchez Pedregal

Victor M. Sanchez Pedregal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optically active carbonates as precursors of (+)-zopiclone
    Patent number: 6969767
    Abstract: In the present invention new compounds of formula II, in enantiomerically enriched forms, are described for the first time, where R1 is chloroalkyl. The present invention also includes several new enzymatic processes for the resolution of the enantiomers of the aforementioned carbonates of formula II from the corresponding racemic mixture. The transformation of these carbonates into zopiclone enantiomerically enriched, constitutes an additional aspect of the invention.
    Type: Grant
    Filed: April 2, 2003
    Date of Patent: November 29, 2005
    Assignees: Universidad de Oviedo, Astur Pharma, S.A.
    Inventors: Miguel Bayod Jasanada, Victor M. Sanchez Pedregal, Vicente Gotor Santamaria, M. Rosario Brieva Collado, Laura Fernandez Solares, Monica Diaz Sierra, Jose Manuel Guisan Seijas, Jose Miguel Palomo Carmona, Roberto Fernandez-Lafuente
  • Optically pure paroxetine precursors
    Publication number: 20040167163
    Abstract: A biocatalytic process to obtain optically enriched precursors of trans-4-(4-fluorophenyl)-3-hydroxymethylpiperidines, based on the enzymatic resolution of racemic derivatives of general formula III (where R3 is preferably phenyl or benzyl) using cyclic anhydrides or the Meldrum's acid (2,2-dimethyl-1,3-dioxane-4,6-dione) as acylating agents of the hydroxyl group. Depending on the enzyme and the chosen reaction conditions, either of the two enantiomers may be obtained with high enantiomeric purity. These compounds are important intermediates in the synthesis of the paroxetine anti-depressive agent.
    Type: Application
    Filed: December 18, 2003
    Publication date: August 26, 2004
    Inventors: Miguel Bayod Jasanada, Victor M. Sanchez Pedregal, Vicente Gotor Santamaria, Gonzalo De Gonzalo Calvo, M. Rosario Brieva Collado