Patents by Inventor Victor Manuel Luna Pineda

Victor Manuel Luna Pineda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimeric and trimeric proteins based on the FimH, CsgA, and PapG adhesins of uropathogenic
    Patent number: 11718649
    Abstract: The present invention is based on the fusion of FimH, CsgA and PapG adhesins (type 1 Fimbriae, curli and P, respectively) to generate biomolecules that can be used as vaccines against UTIs. Briefly, the invention is based on the design of a fusion template gene fimH-csgA-papG-fimH-csgA and defined as fcpfc to generate the different combinations of monomeric [FimH, CsgA and PapG], dimeric [FimH-CsgA (FC), CsgA-PapG (CP) and PapG-FimH (PF)] and trimeric (FimH-PapG-CsgA (FCP), PapG-CsgA-FimH (PCF) and CsgA-FimH-PapG (CFP)] proteins. Bioactivity was determined by the antibodies present in UP sera and urine, the quantification in the release of cytokines and adhesion inhibition assays.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: August 8, 2023
    Inventors: Juan Xicohtencatl Cortes, Victor Manuel Luna Pineda
  • DIMERIC AND TRIMERIC PROTEINS BASED ON THE FIMH, CSGA, AND PAPG ADHESINS OF UROPATHOGENIC ESCHERICHIA COLI
    Publication number: 20200369732
    Abstract: The present invention is based on the fusion of FimH, CsgA and PapG adhesins (type 1 Fimbriae, curli and P, respectively) to generate biomolecules that can be used as vaccines against UTIs. Briefly, the invention is based on the design of a fusion template gene fimH-csgA-papG-fimH-csgA and defined as fcpfc to generate the different combinations of monomeric [FimH, CsgA and PapG], dimeric [FimH-CsgA (FC), CsgA-PapG (CP) and PapG-FimH (PF)] and trimeric (FimH-PapG-CsgA (FCP), PapG-CsgA-FimH (PCF) and CsgA-FimH-PapG (CFP)] proteins. Bioactivity was determined by the antibodies present in UP sera and urine, the quantification in the release of cytokines and adhesion inhibition assays.
    Type: Application
    Filed: October 11, 2018
    Publication date: November 26, 2020
    Inventors: Juan Xicohtencatl Cortes, Victor Manuel Luna Pineda