Patents by Inventor Victor N. Nussenzweig

Victor N. Nussenzweig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protective peptide antigen
    Patent number: 5614194
    Abstract: Described is a antigen and antigenic amino acid sequence consisting of repeating units of the immunodominant epitope region of the circumsporozoite surface protein of a parasite of the genus Plasmodium. Also described is a related fusion protein produced by a recombinant microorganism and a vaccine for immunizing mammals against malaria.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 25, 1997
    Assignee: New York University
    Inventors: David R. Colman, Joan Ellis, G. Nigel Godson, Ruth S. Nussenzweig, Victor N. Nussenzweig, Pamela S. Svec, Fidel Zavala
  • Cross-reactive and protective epitopes of circumsporozoite proteins
    Patent number: 5178861
    Abstract: Disclosed is a peptide antigen comprising an amino acid sequence of a non-repetitive epitope of the circumsporozoite protein of a sporozoite of the genus plasmodium said peptide having the property of eliciting formation of antibodies that bind to said nonrepetitive epitope on the sporozoite surface said peptide being synthetic, purified and substantially shorter in length than said protein.
    Type: Grant
    Filed: June 22, 1989
    Date of Patent: January 12, 1993
    Assignee: New York University
    Inventors: Ulises Vergara, Andres Ruiz, Arturo Ferreira, Ruth S. Nussenzweig, Victor N. Nussenzweig
  • Immunogenic peptide corresponding to P. vivax CS protein
    Patent number: 4957869
    Abstract: Disclosed are peptides comprising the amino acidsAsp-Arg-Ala-X-Gly-Gln-Pro-Ala-Glywherein X represents Asp or Ala, said peptides eleciting antibodies against the P. vivax circumsporozoite protein. Also disclosed are DNA sequences coding for such peptides.
    Type: Grant
    Filed: April 5, 1988
    Date of Patent: September 18, 1990
    Assignee: New York University
    Inventors: David E. Arnot, Vincenzo Enea, Ruth S. Nussenzweig, Victor N. Nussenzweig
  • Cross-reactive and protective epitopes of CS
    Patent number: 4915942
    Abstract: Synthetic peptides containing non-repeating epitopes of circumsporozoite derived protein antigen and which are substantially shorter in length than the intact antigen are disclosed. The peptides when administered to a host raise antibodies in that host that will bind to the circumsporozoite antigen on the parasite. Vaccines based upon these peptides, as well as means of raising antibodies to circumsporozoite antigens using the synthetic peptides are also disclosed.
    Type: Grant
    Filed: October 26, 1987
    Date of Patent: April 10, 1990
    Assignee: New York University
    Inventors: Ulises Vergara, Andres Ruiz, Arturo Ferreira, Ruth S. Nussenzweig, Victor N. Nussenzweig
  • Immunodominant epitope of the circumsporozoite surface protein
    Patent number: 4769235
    Abstract: Disclosed are peptides the sequence of which defines an immunodominant epitope from the repetitive immunodominant epitope region of the circumsporozoite (CS) protein of a member of the genus Plasmodium, the sequence of the peptide being shorter in length than the repeating unit of the CS protein.
    Type: Grant
    Filed: January 28, 1985
    Date of Patent: September 6, 1988
    Assignee: New York University
    Inventors: David H. Schlesinger, Victor N. Nussenzweig