Patents by Inventor Victor Nikolaychik

Victor Nikolaychik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150335793
    Abstract: Devices and methods for reducing, eliminating, preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis. A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses.
    Type: Application
    Filed: August 4, 2015
    Publication date: November 26, 2015
    Inventors: Sriram Iyer, Nicholas Kipshidze, Victor Nikolaychik, Gary Roubin
  • Patent number: 9132099
    Abstract: Devices and methods for reducing, eliminating, preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis. A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: September 15, 2015
    Assignee: VASCULAR THERAPIES, INC.
    Inventors: Sriram Iyer, Nicholas Kipshidze, Victor Nikolaychik, Gary Roubin
  • Publication number: 20080091263
    Abstract: This invention is a prosthetic device generally placed on the outside surface of the vessel or graft which then elutes antiproliferative drugs or agents from a drug-eluting matrix material. Methods of perivascular antiproliferative drug administration also are disclosed.
    Type: Application
    Filed: October 31, 2007
    Publication date: April 17, 2008
    Inventors: Sriram Iyer, Nicholas Kipshidze, Victor Nikolaychik
  • Publication number: 20050004158
    Abstract: Devices and methods for reducing, eliminating, preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis. A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses.
    Type: Application
    Filed: June 18, 2004
    Publication date: January 6, 2005
    Applicant: Vascular Therapies LLC
    Inventors: Sriram Iyer, Nicholas Kipshidze, Victor Nikolaychik, Gary Roubin
  • Patent number: 5660873
    Abstract: A method is provided for forming fibrin coatings on a substrate, such as device for implantation in a body. The fibrin coatings are dried to provide a fibrin coating having the ability to be stored for extended periods before use. To provide coatings having high shear force resistance, the substrate is contacted first with thrombin and second with fibrinogen.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: August 26, 1997
    Assignee: Bioseal, Limited Liability Corporaton
    Inventors: Victor Nikolaychik, Nicholas N. Kipshidze, John E. Baker