Abstract: A computer-aided method for adapting a multi-block mesh topology of an object (11) to a modification in its geometry resulting from an operation defined in respect to some spatial directions, the method being used in the design of said object (11) by means of numerical simulation in structured meshes, comprising the following steps: a) providing the starting geometry (21) and mesh topology description (31); b) finding key points (25); c) finding the set of key vertexes placed at said key points (25); d) finding all the reference vertexes seeking for the vertexes connected to the key vertexes along said spatial directions; e) performing the geometrical operation and obtaining the adapted mesh topology moving said set of key vertexes to the position determined by the modified geometry (23) and the rest of vertexes proportionally to the displacement of the corresponding key vertex. The invention also refers to a system for carrying out said method.