Abstract: A method for the preparation of pharmaceutical dosage forms comprising multiple powdered active ingredients, in a preferred embodiment, said method comprising the steps of mixing said active ingredients and at least one chosen excipient so as to obtain a powdered mixture; compacting said powdered mixture in a roller-compactor apparatus to obtain a compacted product; breaking and sieving said compacted product to a chosen mesh size to obtain similar sized granules; preferably dry mixing said granules with at least on chosen excipient so as to obtain a granular mixture; forming said granular mixture into unitary dosage forms.

Abstract: A pointing device employs a panel mounted at an opening in a keyboard of a computer, such as a portable computer with a hinged display screen. The panel is mounted with freedom to move in two dimensions. A knob projecting from atop the panel has an indicating pushbutton. A sensor mounted adjacent to the panel can produce a motion signal in response to motion of the panel. The panel may be mounted with freedom to rise above the sensor and move in the two dimensions without actuating the sensor. Also, a limit detector may be mounted near the opening to sense arrival of the knob at a border of the opening. A controller coupled to the indicating button and the sensor can provide an encoded signal signifying the motion signal and actuation of the indicating button, and if employed, the limit detector.