Patents by Inventor Victor T. Bandurco

Victor T. Bandurco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted amino acids as erythropoietin mimetics
    Patent number: 7384979
    Abstract: This invention relates to a series of substitituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoietin receptor and compete with the natural ligand for binding to this receptor.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: June 10, 2008
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Peter J. Connolly, William V. Murray, Steven K. Wetter, Sigmond Johnson, Victor T. Bandurco, Jacqueline Bussolari
  • Substituted amino acids as erythropoietin mimetics
    Patent number: 7153869
    Abstract: This invention relates to a series of substitituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoietin receptor and compete with the natural ligand for binding to this receptor.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: December 26, 2006
    Inventors: Peter J. Connolly, Victor T. Bandurco, Steven K. Wetter, Sigmond Johnson, Jacqueline Bussolari, William V. Murray
  • Substituted amino acids as erythropoietin mimetics
    Publication number: 20040248815
    Abstract: This invention relates to a series of substitituted amino acids of Formula I 1
    Type: Application
    Filed: March 12, 2004
    Publication date: December 9, 2004
    Applicant: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Peter J. Connolly, Victor T. Bandurco, Steven K. Wetter, Sigmond Johnson, Jacqueline Bussolari, William V. Murray
  • Substituted amino acids as erythropoietin mimetics
    Patent number: 6750369
    Abstract: This invention relates to a series of substituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoietin receptor and compete with the natural ligand for binding to this receptor.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: June 15, 2004
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Peter J. Connolly, Victor T. Bandurco, Steven K. Wetter, Sigmond Johnson, Jacqueline Bussolari, William V. Murray
  • Substituted amino acids as erythropoietin mimetics
    Publication number: 20020016350
    Abstract: This invention relates to a series of substitituted amino acids of Formula I 1
    Type: Application
    Filed: August 10, 2001
    Publication date: February 7, 2002
    Inventors: Peter J. Connolly, Victor T. Bandurco, Steven K. Wetter, Sigmond Johnson, Jacqueline Bussolari, William V. Murray
  • Substituted amino acids as erythropoietin mimetics
    Patent number: 6310078
    Abstract: This invention relates to a series of substituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoietin receptor and compete with the natural ligand for binding to this receptor.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: October 30, 2001
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Peter J. Connolly, Victor T. Bandurco, Steven K. Wetter, Sigmond Johnson, Jacqueline Bussolari, William V. Murray
  • Substituted triazoles as angiotensin II inhibitors
    Patent number: 5508419
    Abstract: This invention relates to novel bis-biphenyl substituted 3-mercapto-1,2,4-tetrazoles and to pharmaceutically acceptable salts thereof.The compounds are angiotensin II receptor antagonists, and are useful in treating hypertension (lowering high blood pressure), congestive heart failure, elevated ocular pressure, cerebral stroke, angina, cardiac insufficiency, myocardial infarction or diabetic nephropathy.The invention also relates to a pharmaceutical composition comprising a compound of the invention, a method of treating a physiological condition in a mammal that is mediated by angiotensin II which comprises administering to the mammal an effective amount of a compound of the invention, and novel processes for preparing the compounds of the invention.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: April 16, 1996
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, William V. Murray, Michael P. Wachter, Charles F. Schwender
  • Substituted triazoles as angiotensin II inhibitors
    Patent number: 5347011
    Abstract: This invention relates to novel bis-biphenyl substituted 3-mercapto-1,2,4-tetrazoles and to pharmaceutically acceptable salts thereof.The compounds are angiotensin II receptor antagonists, and are useful in treating hypertension (lowering high blood pressure), congestive heart failure, elevated ocular pressure, cerebral stroke, angina, cardiac insufficiency, myocardial infarction or diabetic nephropathy.The invention also relates to a pharmaceutical composition comprising a compound of the invention, a method of treating a physiological condition in a mammal that is mediated by angiotensin II which comprises administering to the mammal an effective amount of a compound of the invention, and novel processes for preparing the compounds of the invention.
    Type: Grant
    Filed: June 7, 1993
    Date of Patent: September 13, 1994
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, William V. Murray, Michael P. Wachter, Charles F. Schwender
  • Substituted triazoles as angiotensin II inhibitors
    Patent number: 5240953
    Abstract: This invention relates to novel bis-biphenyl substituted 3-mercapto-1,2,4-tetrazoles and to pharmaceutically acceptable salts thereof.The compounds are angiotensin II receptor antagonists, and are useful in treating hypertension (lowering high blood pressure), congestive heart failure, elevated ocular pressure, cerebral stroke, angina, cardiac insufficiency, myocardial infection or diabetic nephropathy.The invention also relates to pharmaceutical composition comprising a compound of the invention, a method of treating a physiological condition in a mammal that is mediated by angiotensin II which comprises administering to the mammal an effective amount of a compound of the invention, and novel processes for preparing the compounds of the invention.
    Type: Grant
    Filed: January 30, 1992
    Date of Patent: August 31, 1993
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, William V. Murray, Michael P. Wachter, Charles F. Schwender
  • Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones
    Patent number: 4804756
    Abstract: A method for preparing 5,6-dialkoxy-4-alkyl-quinazolinones is described. The 5,6-dialkoxy-4-alkyl-quinazolinones are active cardiotonic agents.
    Type: Grant
    Filed: March 28, 1988
    Date of Patent: February 14, 1989
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Robert A. Mallory, Jeffery B. Press
  • Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones
    Patent number: 4751304
    Abstract: A method for preparing 5,6-dialkoxy-4-alkyl-quinazolinones is described. The 5,6-dialkoxy-4-alkyl-quinazolinones are active cardiotonic agents.
    Type: Grant
    Filed: September 26, 1984
    Date of Patent: June 14, 1988
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Robert A. Mallory, Jeffery B. Press
  • Substituted 3-(4-phenyl-1-piperazinyl)alkylquinazolin-2,4-(1H,3H) diones, methods of preparation, compositions and method of use
    Patent number: 4711883
    Abstract: Novel substituted-3-(4-phenyl-1-piperazinyl)alkyl quinazolin-2,4-(1H,3H)diones are described. These compounds are useful as antihypertensive agents.
    Type: Grant
    Filed: September 30, 1985
    Date of Patent: December 8, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Charles F. Schwender, Robert Falotico, Alfonso J. Tobia
  • Substituted 5,6-dialkoxyquinazoline derivatives
    Patent number: 4672116
    Abstract: Quinazoline derivatives having an oxy substituent in 5 and 6 positions are described. The novel quinazoline derivatives are useful as cardiotonic agents.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: June 9, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, John H. Dodd, Robert Falotico, Charles F. Schwender, Alfonso J. Tobia
  • 5,6-dialkoxy-4-imino-2(1H)quinazolinone derivatives
    Patent number: 4668787
    Abstract: Quinazolinone derivatives having an oxy substituent in the 5- and 6-positions are disclosed. The quinazolinone derivatives are useful as cardiovascular agents.
    Type: Grant
    Filed: December 20, 1985
    Date of Patent: May 26, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, Robert Falotico, Charles F. Schwender, Alfonso J. Tobia
  • Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
    Patent number: 4656267
    Abstract: The synthesis of substituted 2(1H)-quinazolinone-1-alkanoic acids and their esters is described. The novel quinazolinones are renal vasodilators and as such reduce vascular resistance to renal blood flow. The quinazolinones are useful as cardiovascular agents.
    Type: Grant
    Filed: July 2, 1984
    Date of Patent: April 7, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Seymour D. Levine, Dennis M. Mulvey, Alfonso J. Tobia
  • Substituted quinazolinediones
    Patent number: 4639518
    Abstract: The synthesis of 5,6-dioxy substituted quinazolinediones is described. The novel quinazolinediones are useful as cardiotonic agents.
    Type: Grant
    Filed: September 24, 1984
    Date of Patent: January 27, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, Donald W. Combs, Robert Falotico, Alfonso J. Tobia
  • Process for the preparation of 8-halo-5,6-dialkoxyquinazoline-2,4-diones and their salts
    Patent number: 4634769
    Abstract: A process for the preparation of 8-halo-5,6-dialkoxyquinazoline-2,4-diones and their metal salts is described. The diones are active cardiotonic agents.
    Type: Grant
    Filed: September 25, 1984
    Date of Patent: January 6, 1987
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Robert A. Mallory, Jeffrey B. Press, Harvey M. Werblood
  • Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids
    Patent number: 4631283
    Abstract: The synthesis of substituted quinazolinones is described. The novel quinazolinones are renal vasodilators and thereby increase renal blood flow, and are useful as cardiovascular agents.
    Type: Grant
    Filed: August 27, 1984
    Date of Patent: December 23, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Seymour D. Levine, Dennis M. Mulvey, Alfonso J. Tobia
  • 4-alkyl-5,6-methylenedioxy-2-1[H]-quinazolinones useful as cardiotonic agents
    Patent number: 4617392
    Abstract: 4-Alkyl-5,6-, 6,7-methylenedioxy-2-1[H]-quinazolinones are prepared from 2,3-methylenedioxyacetophenones. The 4-alkyl-5,6-, 6,7-methylenedioxy-2-1[H]-quinazolinones are active as cardiotonic agents.
    Type: Grant
    Filed: September 29, 1983
    Date of Patent: October 14, 1986
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Victor T. Bandurco, Stanley C. Bell, Donald W. Combs, Robert Falotico
  • 3,4-Dialkoxy-2-alkylcarbonyl analino compounds
    Patent number: 4556739
    Abstract: A process for preparing 4-alkyl-2(1H)quinazolinone-1-alkanoic acid derivatives is described. The 4-alkyl-2(1H)quinazolinones are useful as cardiovascular agents.
    Type: Grant
    Filed: July 2, 1984
    Date of Patent: December 3, 1985
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Ramesh M. Kanojia, Victor T. Bandurco, Seymour D. Levine, Dennis M. Mulvey, Alfonso J. Tobia