Abstract: The present invention is directed to novel human DNA sequences encoding calcium sensitive potassium channel subunits ?2, ?3a, ?3b, ?3c, and ?3d, the proteins encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and agonists of calcium sensitive potassium channels containing human ?2, ?3a, ?3b, ?3c, or ?3d subunits and inhibitors and agonists of ?3 gene transcription.

Abstract: Disclosed herein are novel nucleic acid molecules encoding murine low-voltage activated calcium channel proteins, designated-?1H, encoded proteins, vectors, host cells transformed therewith, as well as pharmaceutical compositions. Methods of using any of the foregoing, e.g., methods for screening for candidate agonists or antagonists utilizing the novel protein isoforms are also disclosed.

Abstract: The present invention is directed to novel human DNA sequences encoding calcium sensitive potassium channel subunits ?2, ?3a, ?3b, ?3c, and ?3d, the proteins encoded by the DNA sequences, vectors comprising the DNA sequences, host cells containing the vectors, and methods of identifying inhibitors and agonists of calcium sensitive potassium channels containing human ?2, ?3a, ?3b, ?3c, or ?3d subunits and inhibitors and agonists of ?3 gene transcription.