Patents by Inventor Victoria Arena DE SOUZA

Victoria Arena DE SOUZA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230346885
    Abstract: The present invention relates to novel peptides derived from various target proteins, complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: December 9, 2022
    Publication date: November 2, 2023
    Inventors: Alex Powlesland, Alfred Lim, Alina Popa, Andrew Brooks, Benjamin Oestringer, Chandramouli Reddy Chillakuri, Christopher Sayer, Dhaval Jaykant Sangani, Elena Galfre, Fiona Chester, Garret Keating, Graham Anthony Hood, Izabela Bombik, Johanne Pentier, Maurits Kleijnen, Meidai Sun, Nicole Mai, Philip Addis, Pietro Dellacristina, Sarah Gilgunn, Victoria Arena De Souza
  • Publication number: 20230054274
    Abstract: The present invention provides a stabilised peptide-MHC (pMHC) complex, such as a peptide-HLA-E complex. The complex has a non-native linkage, such as a disulphide bond, between the C terminal anchor residue of the peptide, and an amino acid residue in the F pocket of the MHC binding groove.
    Type: Application
    Filed: July 1, 2020
    Publication date: February 23, 2023
    Inventors: Thomas Holberg BLICHER, Victoria Arena DE SOUZA
  • Publication number: 20210322528
    Abstract: The present invention relates to novel peptides derived from Neuropeptide S Receptor (NPSR1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: April 29, 2021
    Publication date: October 21, 2021
    Inventors: Alex POWLESLAND, Victoria Arena DE SOUZA, Chandramouli CHILLAKURI, Dhaval SANGANI, Graham HOOD, Benjamin OESTRINGER
  • Publication number: 20180339027
    Abstract: The present invention relates to novel peptides derived from Neuropeptide S Receptor (NPSR1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
    Type: Application
    Filed: November 23, 2016
    Publication date: November 29, 2018
    Inventors: Alex POWLESLAND, Victoria Arena DE SOUZA, Chandramouli CHILLAKURI, Dhaval SANGANI, Graham HOOD, Benjamin OESTRINGER